Dear Editor,
The report on “Salivary Gland Scintigraphy in the Evaluation of Salivary Gland Dysfunction” is very interesting.[1] Senthilkumar and Sathasivasubramanian concluded that “there was a significant correlation between salivary flow rate and the scintigraphic uptake and excretory ratio.”[1] In fact, there is a previous similar report confirmed the good diagnostic protery of salivary gland scintigraphy.[2] Nevertheless, the false positive of the technique can be expected.[3] Salanci and Ergün noted that “bilateral radioactivity absence is observed usually due to drugs or radiopharmaceutical storage conditions.”[3] In case of existed salivary tumor, Yoshikai et al. noted that “adenoid cystic carcinomas and pleomorphic adenomas were the principal sources of false negative and false positive results, respectively.”[4]
References
- 1.Senthilkumar B, Sathasivasubramanian S. The role of salivary gland scintigraphy in the evaluation of salivary gland dysfunction in uncontrolled type II diabetic patients. World J Nucl Med. 2013;12:94–100. doi: 10.4103/1450-1147.136733. [DOI] [PMC free article] [PubMed] [Google Scholar]
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- 3.Salanci BV, Ergün EL. Patterns of salivary gland uptake in I-131 MIBG scintigraphy. Rev Esp Med Nucl. 2006;25:198–201. doi: 10.1157/13088418. [DOI] [PubMed] [Google Scholar]
- 4.Yoshikai T, Ishimaru J, Satoh T, Inokuchi A, Kudo S. The limitations of gallium scintigraphy in the differentiation between benign and malignant salivary gland mass lesions. Nucl Med Commun. 2003;24:657–62. doi: 10.1097/00006231-200306000-00007. [DOI] [PubMed] [Google Scholar]