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. Author manuscript; available in PMC: 2015 Feb 23.
Published in final edited form as: Echocardiography. 2013 Sep 19;31(3):375–384. doi: 10.1111/echo.12351

Table III. Conventional Echocardiographic Measurements.

Age (weeks)

3 5 7 11 P-value
Morphometric parameters
 Body weight (g) 7.8 ± 0.3 18.3 ± 1.2* 20.7 ± 1.0* 24.5 ± 2.0* <0.01
 Tibia length (mm) 11.3 ± 0.1 14.8 ± 0.2* 16.1 ± 0.1* 16.1 ± 0.9* <0.01
 LV mass (mg) (necropsy) 27 ± 1 61 ± 4* 72 ± 6* 84 ± 7* <0.01
 LV mass (mg) (ECHO) 28.4 ± 5.9 41.9 ± 6.8 73.7 ± 12.7 79.8 ± 18.2 <0.01
Conventional echocardiographic measurements
 Ejection fraction (%) 75 ± 1 70 ± 3 60 ± 1* 61 ± 2* <0.01
 Fractional shortening (%) 44 ± 1 39 ± 2 33 ± 2* 34 ± 2* <0.01
 LVEDD (mm) 2.7 ± 0.1 3.5 ± 0.1* 4.3 ± 0.1* 4.0 ± 0.2* <0.01
 LVESD (mm) 1.5 ± 0.04 2.1 ± 0.10* 2.9 ± 0.1* 2.7 ± 0.2* <0.01
 LVPWd (mm) 0.4 ± 0.04 0.5 ± 0.04 0.6 ± 0.03* 0.6 ± 0.02* <0.01

LV = left ventricle; LVEDD = left ventricle end-diastolic dimension; LVESD = left ventricular end-systolic dimension; LVPWd = left ventricular posterior wall thickness.

*

P < 0.01 as compared to 3 weeks.

LV mass calculated from echocardiographic measurements.