Video 4. ERK activation waves under MMP inhibitor treatment.
A Time-lapse video of an Eisuke mouse subjected to epithelial wounding and 2.0 nanomole TAPI-1 treatment 12 hr before imaging. The FRET/CFP ratio is shown by gold pseudo-colours (right). Images were acquired every 5 min. The area of the viewfield is 0.213 mm2.