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. 1974 Nov;71(11):4612–4616. doi: 10.1073/pnas.71.11.4612

Mitochondrial Genetics in Bakers' Yeast: A Molecular Mechanism for Recombinational Polarity and Suppressiveness

Philip S Perlman 1, C William Birky Jr 1
PMCID: PMC433938  PMID: 4612525

Abstract

Recombinational polarity and suppressiveness are two well-known but puzzling cytoplasmic genetic phenomena in bakers' yeast, Saccharomyces cerevisiae. Little progress has been made in characterizing the underlying molecular mechanisms of these phenomena. In this paper we describe a molecular model for recombinational polarity that is compatible with the available genetic evidence. The model stresses the role of small deletions and excision/repair processes in otherwise canonical recombinational events. According to the model, both phenomena require recombination and may share mechanistic elements.

Keywords: mitochondrial DNA, Saccharomyces cerevisiae

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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