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. 1974 Dec;71(12):5014–5016. doi: 10.1073/pnas.71.12.5014

The Presence of I-Region-Associated Antigens on B Cells in Molecules Distinct from Immunoglobulin and H-2K and H-2D

Emil R Unanue *, Martin E Dorf *, Chella S David †, Baruj Benacerraf *
PMCID: PMC434030  PMID: 4140515

Abstract

The distribution of I-region-associated antigenic specificities in murine lymphoid cells was studied by immunofluorescence. The antigens were mostly represented in B cells and in macrophages. The complexes of I-anti-I-region-associated antigens were found to be distributed throughout the lymphocyte surface both at 4° and 37°. In about two-thirds of the lymphocytes the complexes redistributed into caps after incubation with a second ligand (an anti-mouse immunoglobulin). The I-region specificities were in molecules distinct from immunoglobulin or from the molecules coded by the H-2K and H-2D regions.

Keywords: lymphocytes, histocompatibility antigens, surface molecules, immunogenetics

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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