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. 1974 Oct;71(10):3988–3992. doi: 10.1073/pnas.71.10.3988

Location of the Spike Glycoproteins in the Semliki Forest Virus Membrane

Henrik Garoff 1, Kai Simons 1
PMCID: PMC434312  PMID: 4530279

Abstract

Labeling experiments with formyl-[35S]-methionyl sulfone methylphosphate and crosslinking studies with dimethylsuberimidate suggest that the spike glycoproteins of Semliki Forest virus extend through the viral membrane into close contact with the nucleocapsid. Based on this finding, we present a mechanism for the formation of virus-specific patches in the host cell plasma membrane during virus assembly.

Keywords: formyl-[35S]methionyl sulfone methylphosphate, dimethylsuberimidate, peptide mapping, sodium dodecyl sulfate-gel electrophoresis

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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