Table 1. Characteristics of participants classified by diagnostic group.
Means (M) and standard deviations (SD) are listed for each group unless otherwise noted.
|
Healthy
Controls |
FTD
(subtypes combined) |
bvFTD | svPPA | nfvPPA | |
|---|---|---|---|---|---|
| n | 34 | 96 | 47 | 33 | 16 |
| Age | 64.9 (9.3) | 61.9 (7.3) | 59.6 (7.5) | 63.2 (5.3) | 65.9 (7.9) |
| Sex: % Female | 50.0 | 39.6 | 31.9 | 39.4 | 62.5 |
| Education | 17.3 (2.2) | 15.8 (2.8) | 16.2 (2.6) | 15.8 (3.1) | 14.8 (2.5) |
| Handedness: % Right- handed |
91.2 | 89.6 | 93.6 | 81.8 | 93.8 |
| Study wave: % Wave 1 | 47.1 | 42.7 | 51.1 | 45.5 | 12.5 |
| CDR Total | 0.0 (0.1) | 0.9 (0.6) | 1.2 (0.6) | 0.8 (0.5) | 0.5 (0.5) |
| CDR-SB | 0.0 (0.1) | 5.1 (3.3) | 6.7 (2.8) | 3.9 (2.8) | 2.6 (3.4) |
| MMSE | 29.7 (0.5) | 24.4 (6.1) | 25.3 (4.9) | 23.8 (6.7) | 22.8 (7.7) |
| California Verbal Learning Test Short Form 10-Minute Recall (/9)† |
7.1 (1.8) | 3.5 (2.8) | 4.0 (2.7) | 2.3 (2.5) | 4.7 (3.2) |
| Benson Figure Copy 10- Minute Recall (/17) |
12.2 (2.6) | 7.3 (4.7) | 7.4 (4.5) | 6.4 (4.8) | 9.7 (4.4) |
| Modified Trails (correct lines per minute) |
35.0 (10.2) | 17.7 (12.6) | 16.4 (13.8) | 21.3 (10.9) | 12.2 (10.0) |
| Modified Trails Errors | 0.33 (0.7) | 1.4 (1.9) | 1.9 (2.2) | 0.4 (0.6) | 2.2 (2.1) |
| Phonemic Fluency (# correct in 60 seconds) |
16.6 (6.7) | 7.7 (5.6) | 8.7 (7.1) | 7.1 (2.8) | 5.0 (3.2) |
| Semantic Fluency (# correct in 60 seconds) |
23.2 (5.2) | 10.9 (5.0) | 12.4 (4.9) | 8.7 (4.1) | 10.3 (5.6) |
| Design Fluency Correct (# correct in 60 seconds) |
11.0 (3.1) | 6.8 (3.5) | 6.4 (3.6) | 7.0 (3.5) | 7.6 (3.6) |
| Design Fluency Repetitions | 1.4 (1.8) | 3.8 (5.1) | 5.1 (6.2) | 2.1 (2.8) | 2.7 (3.0) |
| Digits Backward | 5.5 (1.5) | 4.3 (1.5) | 4.3 (1.6) | 4.4 (1.1.) | 3.6 (1.8) |
| Benson Figure Copy (/17) | 15.7 (1.0) | 14.9 (1.6) | 14.6 (1.7) | 15.3 (1.5) | 15.1 (1.6) |
| Calculations (/5) | 5.0 (0.2) | 4.2 (1.2) | 3.9 (1.4) | 4.7 (0.5) | 4.3 (1.3) |
| Boston Naming Test Spontaneous Correct (/15) |
14.7 (0.6) | 10.1 (4.6) | 12.5 (3.0) | 5.7 (3.9) | 11.8 (3.5) |
| Peabody Picture Vocabulary Test (/16) |
15.7 (0.6) | 12.4 (3.9) | 14.4 (2.0) | 8.9 (4.2) | 13.7 (2.3) |
†
19/34 healthy controls got the California Verbal Learning Test-II (16-word list) instead of the Short-Form. Their performance on the 20-minute delay was also in the average range (M= 13.3, SD= 2.2). bvFTD = behavioral variant frontotemporal dementia, svPPA = semantic variant primary progressive aphasia, nfvPPA = non-fluent variant primary progressive aphasia, MMSE = Mini-Mental State Examination, CDR Total = Clinical Dementia Rating Total score, and CDR-SB = Clinical Dementia Rating Sum of Boxes.