Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2015 Mar 5.

Published in final edited form as: Pancreatology. 2012 Feb 25;12(2):113–118. doi: 10.1016/j.pan.2012.02.014

Table 3.

Genotypes of TNFA promoter in AP patients with and without MODS

		non-MODS AP (n=188)	MODS (n=23)	P value, OR (95%CI)
	Genotype
TNFA-1031	T/T	127 (67.6%)	10 (43.5%)	0.022, 2.7 (1.12–6.51)
TNFA-1031	Minor allele (T/C+C/C)	61 (32.4%)	13 (56.5%)	0.022, 2.7 (1.12–6.51)
	T/C	54 (28.4%)	12 (52.2%)
	C/C	7 (3.7%)	1 (4.3%)
TNFA-863	C/C	147 (78.2%)	13 (56.5%)	0.022, 2.76 (1.12–6.74)
TNFA-863	Minor allele (A/C+A/A)	41 (21.8%)	10 (43.5%)	0.022, 2.76 (1.12–6.74)
	A/C	35 (18.6%)	9 (39.1%)
	A/A	6 (3.2%)	1 (4.3%)
TNFA-857	C/C	153 (81.4%)	18 (78.3%)	0.71, 1.21 (0.42–3.49)
TNFA-857	Minor allele (C/T+T/T)	35 (18.6%)	5 (21.7%)	0.71, 1.21 (0.42–3.49)
	C/T	35 (18.6%)	4 (17.4%)
	T/T	0 (0%)	1 (4.3%)
TNFA-308	G/G	130 (70.6%)^*	17 (73.9%)	0.92, 0.84 (0.31–2.27)
TNFA-308	Minor allele (G/A+A/A)	54 (29.3%)	6 (26.1%)	0.92, 0.84 (0.31–2.27)
	G/A	54 (29.3%)	6 (26.1%)
	A/A	0 (0%)	0 (0%)
TNFA-238	G/G	164 (89.1%)^*	22 (95.7%)	0.54, 0.37 (0.04–2.91)
TNFA-238	Minor allele (G/A+A/A)	20 (10.9%)	1 (4.3%)	0.54, 0.37 (0.04–2.91)
	G/A	19 (10.3%)	1 (4.3%)
	A/A	1 (0.6%)	0 (0%)

^*

In four patients with non-MOD AP, genotypes at −308 and −238 locus could not be determined.