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. 2015 Mar 5;10(3):e0118636. doi: 10.1371/journal.pone.0118636

Correction: Histidine-Rich Glycoprotein Uptake and Turnover Is Mediated by Mononuclear Phagocytes

The PLOS ONE Staff
PMCID: PMC4351069  PMID: 25741998

Fig. 2 is incorrect. The y-axis is incorrectly labeled in Fig. 2G. The authors have provided a corrected version here.

Fig 2. Unusually rapid biodistribution of radiolabeled HRG.

Fig 2

A. Blood kinetics of 125l-albumin, 125l-hHRG and 125l-mHRG in C57BL/6 mice. (n = 4/time point). B. Biodistribution of 125l-hHRG in selected C57BL/6 mouse organs. C. Percentage of radioactivity in blood plasma, associated with a high molecular-weight fraction (>5 kDa). D. Biodistribution of 125l-mHRG in selected organs of naive C57BL/6 mice. E. Liver uptake of 125l-mHRG and 125l-mHRG. F. Biodistribution of 125l-mHRG in selected organs of T241 fibrosarcoma-bearing C57BL/6 mice. G. TCA-precipitable 125l-radioactivity in plasma after 2 h of circulation in naive and tumor-bearing mice injected with 125l-mHRG.

The Fig. 4 legend is incorrect. The third sentence of the Fig. 4 legend should have been omitted. The complete, correct Fig. 4 legend is:

Fig 4. HRG detected by IHC of CRC tumor tissue arrays.

Fig 4

A. Scoring of HRG IHC signals associated with inflammatory cells in CRC arrays from strong to no signal. Statistical analysis; p<0.05 was considered significant. B. Scoring of HRG IHC signals associated with vessels, as above. C. Upper and middle row of panels: Representative images of the HRG IHC signals from the indicated categories at 20× magnification. Lower row of panels: Representative images of the HRC IHC signals in CRC at 60× magnification. Arrows indicate typical vessel-associated HRG signals in normal colorectal tissue (left) and in inflammatory cells in normal tissue (middle) and in stage 2 CRC (right).

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