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. Author manuscript; available in PMC: 2015 Mar 6.
Published in final edited form as: Chemistry. 2013 Sep 3;19(39):12953–12958. doi: 10.1002/chem.201301731

Table 3.

[CoII(Por)]-catalysed trans-selective β-lactam synthesis from αdiazocarbonyl compounds.[a]

graphic file with name nihms667899t3.jpg
Entry Catalyst Diazo Imine Yield [%][b] (trans:cis)
1 [CoII(P1)] R = Et R′ = Me 65 (5a) (>95:5)
2 [CoII(P2)] R = Et R′ = Me 65 (5a) (>95:5)
3 [CoII(P3)] R = Et R′ = Me 67 (5a) (>95:5)
4 [CoII(P1)] R = Et R′ = CH2Ph 50 (5b) (>90:5)
5 [CoII(P1)] R = Et R′ = tBu 55 (5c) (>95:5)
6 [CoII(P1)] R = tBu R′ = Me 66 (5d) (>95:5)
[a]

Stoichiometry EDA:imine = 1:2.

[b]

Isolated yields after column chromatography.