Table 2.

Patient enrolment^* (per-protocol population).

Age at prophylaxis start, years	Current Age, years				Total patients enrolled, n
	12−16 (n = 8)	17−21 (n = 28)	22−26 (n = 43)	27–35 (n = 39)
<2 (primary)	4/5	8/10	9/10	4/10	25
2 – <6 (secondary)	4/5	7/10	5/10	6/10	22
6 – <12 (secondary)	−	12/10	12/25	3/30	27
12 – 18 (secondary)	−	−	7/35	14/35	21
Never (on demand)	0/5	1/10	10/15	12/15	23

^*Unless indicated otherwise, actual/planned enrolment per group is shown.