Table 1B. Characteristics of participants (n=870), aged 40-79 years, across quartiles of HDL cholesterol concentration, 2006 - 2008, Kusatsu, Shiga, Japan.
Characteristic | Quartile of HDL-C | P trend | |||
---|---|---|---|---|---|
| |||||
1 | 2 | 3 | 4 | ||
|
|
|
|
|
|
Age, years | 64.1 ± 9.5 | 63.7 ± 9.5 | 62.2 ± 10.6 | 63.4 ± 10.3 | 0.129 |
Body mass index, kg/m2 | 24.6 ± 3.0 | 23.9 ± 2.8 | 23.0 ± 2.9 | 21.9 ± 2.6 | <0.001 |
SBP, mmHg | 137 ± 17 | 136 ± 19 | 136 ± 18 | 135 ± 23 | 0.168 |
Hypertension, %† | 55.2 | 50.5 | 56.4 | 41.4 | 0.008 |
Diabetes, % (Type 2) | 20.8 | 22.0 | 20.5 | 9.5 | 0.001 |
Current smoker, % | 42.5 | 32.7 | 35.0 | 23.3 | <0.001 |
Alcohol intake (g/day) | 18.4 ± 23.8 | 19.0 ± 24.2 | 27.9 ± 30.0 | 30.9 ± 30.9 | <0.001 |
Triglycerides, mmol/l | 1.91 ± 1.01 | 1.49 ± 1.11 | 1.23 ± 0.63 | 0.96 ± 0.43 | <0.001 |
LDL-C, mmol/l‡ | 3.36 ± 0.85 | 3.47 ± 0.82 | 3.18 ± 0.72 | 3.02 ± 0.79 | <0.001 |
HDL-P, μmol/l | 28.9 ± 4.6 | 32.5 ± 4.2 | 36.4 ± 5.7 | 39.0 ± 7.1 | <0.001 |
Values are mean ± SD, or % (as indicated).
Hypertension is defined as SBP ≥140mmHg or DBP ≥ 90mmHg or use of anti- hypertensive medication. Diabetes is defined as glycated hemoglobin ≥ 6.5% (NGSP) or fasting glucose ≥ 6.99 mmol/l or use of anti-diabetic medication.
LDL-C was calculated by Friedewald equation. [LDL-C (mg/dl) = total cholesterol (mg/dl) - HDL cholesterol (mg/dl) -triglyceride(mg/dl)/5]
Quartiles of HDL-C are as follows (1): 0.67 to 1.19 mmol/l; n=212, (2): 1.22 to 1.45 mmol/l; n=214, (3): 1.46 to 1.78 mmol/l; n=234, and (4): 1.81 to 3.88 mmol/l; n=210. P-values for trend were obtained using linear regression (for continuous variables) or logisitc regression (for categorical variables) as per 1 unit increase in HDL-C.