Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1952 Aug;31(8):756–761. doi: 10.1172/JCI102660

METABOLISM OF PTEROYLGLUTAMIC ACID AND THE CITROVORUM FACTOR IN PATIENTS WITH SCURVY 1,2

George J Gabuzda Jr 1,2,3, Gerald B Phillips 1,2, Robert F Schilling 1,2, Charles S Davidson 1,2
PMCID: PMC436471  PMID: 14955527

Full text

PDF
756

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BROQUIST H. P., STOKSTAD E. L. R., JUKES T. H. Biochemical studies with the "citrovorum factor". J Lab Clin Med. 1951 Jul;38(1):95–100. [PubMed] [Google Scholar]
  2. BROQUIST H. P., STOKSTAD E. L. R., JUKES T. H. Some biological and chemical properties of the citrovorum factor. J Biol Chem. 1950 Jul;185(1):399–409. [PubMed] [Google Scholar]
  3. BURCHENAL J. H., BABCOCK G. M., BROQUIST H. P., JUKES T. H. Prevention of chemotherapeutic effects of 4-amino-N10-methyl-pteroylglutamic acid on mouse leukemia by citrovorum factor. Proc Soc Exp Biol Med. 1950 Aug;74(4):735–737. doi: 10.3181/00379727-74-18031. [DOI] [PubMed] [Google Scholar]
  4. Butler A. M., Cushman M. DISTRIBUTION OF ASCORBIC ACID IN THE BLOOD AND ITS NUTRITIONAL SIGNIFICANCE. J Clin Invest. 1940 May;19(3):459–467. doi: 10.1172/JCI101147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CRAVENS W. W., SNELL E. E. Reversal of aminopterin inhibition in the chick embryo with the Leuconostoc citrovorum factor. Proc Soc Exp Biol Med. 1950 Oct;75(1):43–45. doi: 10.3181/00379727-75-18094. [DOI] [PubMed] [Google Scholar]
  6. DAVIDSON L. S. P., GIRDWOOD R. H. Treatment of pernicious anaemia with Leuconostoc citrovorum factor. Lancet. 1951 Mar 31;1(6657):722–723. doi: 10.1016/s0140-6736(51)92145-9. [DOI] [PubMed] [Google Scholar]
  7. ELLISON R. R., WOLFE S., LICHTMAN H., GINSBERG V., WATSON J. Effect of citrovorum factor in pernicious anemia. Proc Soc Exp Biol Med. 1951 Feb;76(2):366–370. doi: 10.3181/00379727-76-18491. [DOI] [PubMed] [Google Scholar]
  8. JARROLD T., HORRIGAN D., THOMPSON C., VILTER R. W. The hematologic effect of folinic acid (citrovorum factor) in persons with pernicious anemia. Science. 1951 Jun 15;113(2946):688–689. doi: 10.1126/science.113.2946.688. [DOI] [PubMed] [Google Scholar]
  9. MAY C. D., SUNDBERG R. D., SCHAAR F. Comparison of effects of folic acid and folinic acid in experimental megaloblastic anemia. J Lab Clin Med. 1950 Dec;36(6):963–964. [PubMed] [Google Scholar]
  10. MEYER L. M., BRAHIN C. M., SAWITSKY A. Treatment of pernicious anemia with citrovorum factor. Proc Soc Exp Biol Med. 1951 Jan;76(1):86–90. doi: 10.3181/00379727-76-18395. [DOI] [PubMed] [Google Scholar]
  11. NICHOL C. A., WELCH A. D. On the mechanism of action of aminopterin. Proc Soc Exp Biol Med. 1950 Jun;74(2):403–411. doi: 10.3181/00379727-74-17922. [DOI] [PubMed] [Google Scholar]
  12. NICHOL C. A., WELCH A. D. Synthesis of citrovorum factor from folic acid by liver slices; augmentation by ascorbic acid. Proc Soc Exp Biol Med. 1950 May;74(1):52–55. doi: 10.3181/00379727-74-17806. [DOI] [PubMed] [Google Scholar]
  13. SAUBERLICH H. E., BAUMANN C. A. Further studies on the factor required by Leuconostoc citrovorum 8081. J Biol Chem. 1949 Dec;181(2):871–877. [PubMed] [Google Scholar]
  14. SAUBERLICH H. E. The effect of folic acid upon the urinary excretion of the growth factor required by Leuconostoc citrovorum. J Biol Chem. 1949 Dec;181(2):467–473. [PubMed] [Google Scholar]
  15. SCHOENBACH E. B., GREENSPAN E. M., COLSKY J. Reversal of aminopterin and amethopterin toxicity by citrovorum factor. J Am Med Assoc. 1950 Dec 30;144(18):1558–1560. doi: 10.1001/jama.1950.62920180002006a. [DOI] [PubMed] [Google Scholar]
  16. WAISMAN H. A., GREEN M., MUNOZ J. C., RAMENCHIK A., RICHMOND J. B. Role of aureomycin and citrovorum factor in "folic acid" deficiencies. Proc Soc Exp Biol Med. 1951 Feb;76(2):384–388. doi: 10.3181/00379727-76-18498. [DOI] [PubMed] [Google Scholar]
  17. WELCH A. D., NICHOL C. A., ANKER R. M., BOEHNE J. W., 3rd The effect of ascorbic acid on the urinary excretion of citrovorum factor derived from folic acid. J Pharmacol Exp Ther. 1951 Dec;103(4):403–411. [PubMed] [Google Scholar]
  18. WOODRUFF C. W., PETERSON J. C., DARBY W. J. Citrovorum factor and folic acid in treatment of megaloblastic anemia in infancy. Proc Soc Exp Biol Med. 1951 May;77(1):16–18. doi: 10.3181/00379727-77-18662. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES