Table 1.
Demographic and Clinical Characteristics of the Patients at Baseline
| Patient Characteristics | Genotype 2 (N = 23) | Genotype 3 (N = 24) | Total (N = 47) |
|---|---|---|---|
| Age in years, mean (range) | 58 (46-72) | 54 (39-64) | 56 (39-72) |
| Male sex, n (%) | 14 (61) | 18 (75) | 32 (68) |
| Body mass index in kg/m2, mean (SD) | 32 (21-45) | 31 (21-53) | 31 (21-53) |
| Race, n (%) | |||
| White | 22 (96) | 23 (96) | 45 (96) |
| Black/African American | 0 (0) | 1 (4) | 1 (2) |
| Asian | 1 (4) | 0 | 1 (2) |
| Ethnicity, n (%) | |||
| Hispanic/Latino | 11 (48) | 10 (42) | 21 (45) |
| Non-Hispanic/Latino | 12 (52) | 14 (58) | 26 (55) |
| Disease characteristic | |||
| Cirrhosis, n (%) | |||
| No | 9 (39) | 12 (50) | 21 (45) |
| Yes | 14 (61) | 12 (50) | 26 (55) |
| IL28B, n (%) | |||
| CC | 10 (43) | 7 (29) | 17 (36) |
| CT | 10 (44) | 15 (63) | 25 (53) |
| TT | 3 (13) | 2 (8) | 5 (11) |
| Baseline HCV RNA (log10 IU/mL), Mean (SD) | 6.4 (0.7) | 6.0 (0.6) | 6.2 (0.7) |
| Baseline alanine aminotransferase (U/L), Mean (SD) | 91 (54) | 126 (86) | 109 (74) |
| Previous treatment, n (%) | |||
| No response | 2 (9) | 5 (21) | 7 (15) |
| Relapse or breakthrough infection | 21 (91) | 19 (79) | 40 (85) |
BMI, body mass index; SD, standard deviation.