There is an error in Table 2. The value for unadjusted Right ventricle (RV) mass/BAS, gm/m2 in the BOS 0/0p is incorrect. The correct value is 30. Additionally, the value for the unadjusted ejection fraction, % BOS 0/0p is incorrect. The correct value is 64. Please see the corrected Table 2 here. The publisher apologizes for the error.
Table 2. Cardiac magnetic resonance imaging (MRI): unadjusted and adjusted values of cardiac structure and function according to bronchiolitis obliterans (BOS) status*.
| Cardiac MRI measurements | Unadjusted | Adjusted † | |||||
|---|---|---|---|---|---|---|---|
| BOS 1–3 | BOS 0/0p | p | BOS 1–3 | BOS 0/0p | % difference ‡ | p | |
| Left ventricle (LV) | |||||||
| mass / BSA, g/m 2 | 67[62;72] | 77 [71;83] | 0.02 | 70 [67;72] | 75 [73;77] | −7.3 | 0.003 |
| end-diastolic volume / BSA, ml/m 2 | 56 [51;62] | 67 [60;75] | 0.01 | 58 [55;61] | 67 [64;70] | −15.8 | <0.001 |
| end-systolic volume / BSA, ml/m 2 | 22 [19;25] | 24 [21;28] | 0.24 | 22 [21;23] | 24 [23;26] | −9.5 | 0.014 |
| stroke volume /BSA, ml/m 2 | 35 [31;38] | 43 [39;47] | 0.001 | 36 [33;38] | 43 [41;45] | −19.7 | <0.001 |
| ejection fraction, % | 62 [59;65] | 65 [63;67] | 0.18 | 62 [60;63] | 65 [64;66] | −4.4 | 0.002 |
| Right ventricle (RV) | |||||||
| mass / BSA, g/m 2 | 26 [23;28] | 30 [27;33] | 0.03 | 27 [25;29] | 29 [28;31] | −9.2 | 0.02 |
| end-diastolic volume / BSA, ml/m 2 | 56 [51;61] | 65 [58;71] | 0.03 | 57 [54;60] | 64 [62;67] | −13.5 | 0.002 |
| end-systolic volume / BSA, ml/m 2 | 23 [20;25] | 24 [20;27] | 0.61 | 23 [22;24] | 24 [22;25] | −2.6 | 0.47 |
| stroke volume /BSA, ml/m 2 | 33 [30;36] | 41 [37;45] | 0.002 | 34 [32;36] | 41 [39;43] | −21.0 | <0.001 |
| ejection fraction, % | 60 [57;63] | 64 [61;67] | 0.03 | 60 [58;61] | 64 [63;65] | −7.2 | <0.001 |
| Global cardiac mass / BSA, g/m 2 | 93 [87;100] | 107 [98;115] | 0.013 | 97 [92;101] | 104 [101;107] | −7.8 | 0.005 |
| Cardiac output, l/min | 5.0 [4.6;5.4] | 5.5 [4.9;6.1] | 0.14 | 5.1 [4.8;5.4] | 5.4 [5.2;5.7] | −5.9 | 0.08 |
* Values are the mean ± standard deviation [95% confidence interval]. LV = left ventricle; RV = right ventricle; BSA = body surface area; EDV = end diastolic volume; ESV = end systolic volume; EF = ejection fraction; SV = stroke volume.
† Adjusted for systolic and diastolic blood pressures, heart rate, exercise level, days after double lung transplantation, use of anti-hypertensive drugs, GFR, diabetes and age.
‡ Percent difference in the adjusted mean values of the indicated variable for the BOS group compared to the group without BOS.
Reference
- 1. Hinrichs JB, Renne J, Schoenfeld C, Gutberlet M, Haverich A, Warnecke G, et al. (2014) Cardiac Mass and Function Decrease in Bronchiolitis Obliterans Syndrome after Lung Transplantation: Relationship to Physical Activity? PLoS ONE 9(12): e114001 doi: 10.1371/journal.pone.0114001 [DOI] [PMC free article] [PubMed] [Google Scholar]
