Skip to main content
. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Anesthesiology. 2015 Apr;122(4):895–907. doi: 10.1097/ALN.0000000000000593

Table 1.

Growth Curve Modeling of Ipsilateral Mechanical Hypersensitivity in Rats with pSNL

Predictor Parameter Estimate (Lower Bound, Upper Bound) p
Entire population Intercept 2.8432 (1.7691, 3.1972) <0.0001
Entire population Slope 0.2265 (0.1935, 0.2595) <0.0001
Group Intercept
 DβH-saporin
 IgG-saporin		 −0.060
REF		 (−2.3358, 0.8086) 0.3398
Group Slope
 DβH-saporin
 IgG-saporin		 −0.141
 REF		 (−0.2156,−0.1190) <0.0001

Comparison of growth curve parameters for pSNL rats treated with DβH-saporin or IgG-saporin 14 days prior to pSNL surgery. Growth curve analysis of paw withdrawal thresholds (Day 1-70) best fit a linear model giving rise to an intercept (hypersensitivity at time 0) and slope (linear rate of change in pain measure).

DβH = dopamine β hydroxylase; IgG = immunoglobulin G; pSNL= partial spinal nerve ligation; REF = reference value.