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. 2015 Mar 23;10(3):e0121467. doi: 10.1371/journal.pone.0121467

Correction: Genetic Features of Metachronous Esophageal Cancer Developed in Hodgkin’s Lymphoma or Breast Cancer Long-Term Survivors: An Exploratory Study

The PLOS ONE Staff
PMCID: PMC4370447  PMID: 25799111

There are formatting errors in Table 3 in the PDF version of the article. Please see the correct Table 3 here.

Table 3. LOH and MSI status detected in metachronous or sporadic ESCC and EADC patients.

SPORADIC
Patient D3S37273p24.1 D5S21065p12 D5S6235q11.2 D8S11308p23.1 D9S9429p21.3 D9S1719p21.3 D13S26013q13.1 D13S26713q13.2 D17S132317q21.31 D17S132717q21.31
ESCC
01 ● ○ ● ● ○ ● ● Ø MSI ● ●
02 ○ ○ ● Ø ○ Ø Ø ● Ø ○
03 Ø MSI Ø ○ Ø ○ Ø ● ● ○ ●
04 ● Ø ● Ø ● Ø ● Ø ● Ø
05 ● Ø Ø Ø ● ○ Ø ○ Ø Ø
06 ● ○ Ø ○ ○ ● MSI Ø ● ○ ○
07 ● ● Ø ● ● ● Ø ● Ø ●
08 ● Ø ● Ø ● ● ● ○ ● ●
09 ● ● ● ● ● MSI Ø ● ● ● Ø
10 Ø ● ● ● ○ ● ● ● Ø ○
11 ● ○ MSI ○ ○ ○ ○ ○ ○ ○ ○
12 ○ ○ Ø ● ● ● ● Ø ○ Ø
13 ○ ● ● ● ○ ● Ø ● ○ ○
14 ○ ○ ○ ○ ○ ○ ● Ø ○ ○
15 ● Ø Ø ○ ● ● ● ● ○ ●
EADC
01 ● ● ● ○ MSI ● MSI ○ ○ ● Ø Ø
02 ○ ○ Ø ● ○ Ø Ø ● Ø Ø
03 ○ ○ Ø ● ○ ○ Ø ● Ø ○
04 ● Ø ○ ● ○ ○ ○ ● Ø ●
05 Ø ● Ø ● ○ ● Ø ● Ø ●
06 ● MSI Ø MSI ○ MSI Ø MSI ○ ○ MSI ○ ○ MSI ○ MSI ●
07 Ø ● ● Ø ● ● ● ● ● ●
08 ○ Ø ○ ● ● Ø DEL ○ ○ ●
09 Ø ○ ○ Ø ○ ● ○ ○ Ø Ø
10 Ø Ø ○ ● ● ● ● Ø Ø Ø
11 ● ● ● ● ● Ø ● ● ● Ø
Pos/inf (%) 13/20(65) 8/17(47) 10/18(56) 13/18(72) 12/26(46) 12/19(63) 13/18(72) 15/21(71) 6/15(40) 10/17(59)
METACHRONOUS
Patient D3S37273p24.1 D5S21065p12 D5S6235q11.2 D8S11308p23.1 D9S9429p21.3 D9S1719p21.3 D13S26013q13.1 D13S26713q13 D17S132317q21.31 D17S132717q21.31
ESCC
01 ● ○ ● ● ○ ● Ø ● Ø Ø
02 ○ Ø ● Ø MSI Ø ● ○ ● ● Ø
03 ● ● Ø Ø ● ○ Ø ● ○ ○
04 ● ○ Ø ○ ○ Ø Ø ● ○ ○
05 ○ Ø ● ○ ○ Ø ○ Ø ○ ○
06 Ø ● ● Ø ○ ● ● ● ○ ●
07 ● NA NA Ø MSI ● ● ○ NA NA Ø
08 ● ○ Ø ○ ○ ● ○ Ø ○ ○
09 ○ ○ ● Ø ○ ● Ø Ø Ø Ø
10 ● ○ ● Ø ● Ø ○ Ø Ø ○
11 Ø ● ○ ● ○ ○ ● ○ ○ ○
12 ● ● ● ○ ● ● ● Ø Ø Ø MSI
13 Ø ● ● ● ● ● ● ● ○ Ø
14 ● ○ Ø ○ ● ● Ø ○ Ø Ø
EADC
01 ○ ● ● ○ ● MSI ○ ● Ø Ø Ø
02 ○ Ø ○ ○ ○ Ø Ø ○ Ø ○
03 ● ● ○ Ø ○ ● Ø ● Ø ○
04 Ø Ø Ø ● ○ ● ○ ○ ● ○
05 Ø ● ○ ● ● ○ ● ● Ø Ø
06 Ø ● Ø ○ ○ ○ ○ Ø ○ Ø
Pos/inf (%) 9/14(64) 9/15(60) 9/13(69) 5/13(38) 8/19(42) 11/16(69) 6/13(46) 8/12(67) 2/10(20) 1/10(10)
p-value 1 0.50 0.48 0.07 1 1 0.26 1 0.4 0.018

(●) LOH positive; (○) LOH negative; (Ø) uninformative; MSI (positive to microsatellite instability); NA (not amplifiable); DEL: deletion. p-value was calculated using the two-tailed Fisher’s exact test.

Reference

  • 1. Boldrin E, Rumiato E, Fassan M, Cappellesso R, Rugge M, Chiarion-Sileni V, et al. (2015) Genetic Features of Metachronous Esophageal Cancer Developed in Hodgkin’s Lymphoma or Breast Cancer Long-Term Survivors: An Exploratory Study. PLoS ONE 10(1): e0117070 doi:10.1371/journal.pone.0117070 [DOI] [PMC free article] [PubMed] [Google Scholar]

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