Table 3.
Liver and pancreas tested parameters in control and different experimental groups of male rats
| Tested parameters | Animal groups | |||||||
|---|---|---|---|---|---|---|---|---|
| Young group | Adult group | |||||||
| NC | FG | NT | NT + FG | NC | FG | NT | NT + FG | |
| Liver | ||||||||
| TL (mg/g wet tissue) | 74.79 ± 1.58 | 65.55a ± 2.27 (−12.35) | 119.47a ± 4.11 (+59.74) | 87.77ac ± 1.36 (+17.36) | 79.06 ± 1.07 | 72.38b ± 1.35 (−8.45) | 111.75b ± 1.83 (+41.35) | 85.34bd ± 1.36 (+7.94) |
| TC (mg/g wet tissue) | 17.17 ± 0.28 | 13.27a ± 0.41 (−22.71) |
29.35a ± 0.99 (+70.94) |
21.48ac ± 0.49 (+25.10) |
17.15 ± 0.32 | 13.47b ± 0.23 (−21.46) |
23.17b ± 0.46 (+35.10) |
20.98bd ± 0.36 (+22.33) |
| TG (mg/g wet tissue) | 23.61 ± 0.93 | 19.10a ± 0.30 (−19.10) |
39.63a ± 1.12 (+67.85) |
29.46ac ± 0.32 (+24.78) |
25.76 ± 1.05 | 22.26b ± 0.69 (−13.59) |
39.17b ± 1.02 (+52.06) |
29.32bd ± 0.35 (+13.82) |
| PLs (mg/g wet tissue) | 28.83 ± 1.05 | 25.76a ± 0.64 (−10.65) |
44.08a ± 1.36 (+52.90) |
31.79ac ± 0.66 (+10.27) |
31.88 ± 0.87 | 28.95b ± 0.63 (−9.19) |
42.98b ± 0.91 (+34.82) |
32.38d ± 1.13 (+1.57) |
| T. protein (g/g wet tissue) | 1.49 ± 0.02 | 1.76a ± 0.03 (+18.12) |
1.29a ± 0.02 (−13.42) |
1.40ac ± 0.01 (−6.04) |
1.42 ± 0.02 | 1.56b ± 0.02 (+9.86) |
1.24b ± 0.01 (−12.68) |
1.34bd ± 0.01 (−5.63) |
| ALT (μU/g wet tissue) | 46.04 ± 0.23 | 45.88 ± 0.40 (−0.35) |
40.19a ± 0.30 (−12.71) |
45.28c ± 0.24 (−1.65) |
75.02 ± 0.33 | 74.98 ± 0.27 (−0.05) |
65.55b ± 0.55 (−12.62) |
74.33d ± 0.48 (−0.92) |
| AST (μU/g wet tissue) | 48.06 ± 0.30 | 47.91 ± 0.74 (−0.31) |
41.33a ± 0.49 (−14.00) |
45.23ac ± 0.27 (−5.89) |
51.92 ± 0.78 | 51.73 ± 0.46 (−0.37) |
45.58b ± 0.42 (−12.21) |
50.18bd ± 0.60 (−3.35) |
| Glycogen (mg/g wet tissue) | 6.58 ± 0.05 | 7.12a ± 0.06 (+8.21) |
5.86a ± 0.06 (−10.94) |
6.14ac ± 0.07 (−6.69) |
6.75 ± 0.07 | 7.05b ± 0.04 (+4.44) |
6.05b ± 0.07 (−10.37) |
6.30bd ± 0.06 (−6.67) |
| G-6-Pase (μmol/min/g) | 0.11 ± 0.004 | 0.10 ± 0.005 (−9.09) |
0.26a ± 0.008 (+136.36) |
0.15ac ± 0.003 (+36.36) |
0.12 ± 0.005 | 0.12 ± 0.007 (0) |
0.24b ± 0.008 (+100) |
0.14bd ± 0.006 (+16.67) |
| NO (μmol/g wet tissue | 11.93 ± 0.13 | 10.67a ± 0.23 (−10.56) |
24.35a ± 0.19 (+104.11) |
19.06ac ± 0.12 (+59.77) |
10.95 ± 0.27 | 10.12b ± 0.20 (−7.58) |
15.58b ± 0.41 (+42.28) |
12.63bd ± 0.45 (+15.34) |
| Pancreas | ||||||||
| TL (mg/g wet tissue) | 121.96 ± 1.61 | 100.79a ± 0.90 (−17.36) |
197.05a ± 1.96 (+61.57) |
140.50ac ± 0.35 (+15.20) |
152.53 ± 0.60 | 126.99b ± 0.71 (−16.74) |
198.09b ± 0.78 (+29.87) |
155.62bd ± 0.68 (+2.03) |
| TC (mg/g wet tissue) | 15.68 ± 0.49 | 13.22a ± 0.53 (−15.69) |
36.64a ± 1.35 (+133.67) |
16.38c ± 0.48 (+4.46) |
16.28 ± 0.46 | 13.73b ± 0.54 (−15.66) |
28.39b ± 0.91 (+74.39) |
16.95d ± 0.43 (+4.12) |
| TG (mg/g wet tissue) | 71.93 ± 1.51 | 57.84a ± 1.26 (−19.59) |
104.28a ± 3.11 (+44.79) |
88.01ac ± 1.94 +22.36) |
88.80 ± 2.36 | 80.51b ± 1.88 (−9.34) |
108.85b ± 1.64 (+22.58) |
92.12d ± 1.94 (+3.74) |
| PLs (mg/g wet tissue) | 31.75 ± 0.75 | 27.06a ± 0.28 (−14.77) |
50.27a ± 0.47 (+58.33) |
34.64ac ± 0.58 (+9.10) |
32.09 ± 0.30 | 28.95b ± 0.63 (−9.78) |
49.18b ± 0.72 (+53.26) |
32.28d ± 0.19 (+0.59) |
| T. protein (g/g wet tissue) | 2.33 ± 0.04 | 3.20a ± 0.18 (+37.34) |
0.86a ± 0.04 (−63.09) |
2.03ac ± 0.09 (−12.88) |
2.03 ± 0.10 | 2.78b ± 0.13 (+36.95) |
0.91b ± 0.06 (−55.17) |
1.80d ± 0.07 (−11.33) |
| NO (μmol/g wet tissue) | 11.96 ± 0.19 | 10.28a ± 0.09 (−14.05) |
14.76a ± 0.31 (+23.41) |
12.32c ± 0.39 (+3.01) |
11.87 ± 0.04 | 10.33b ± 0.10 (−12.97) |
14.30b ± 0.25 (+20.47) |
12.19d ± 0.11 (+2.70 |
Values are mean ± SE of 6 animals for each group. The values in parentheses are percentage of change from control
Values bearing superscript are significantly different by ANOVA test at p ≤ 0.05
NC normal Control, FG fenugreek, NT nitrate, NT + FG nitrate +fenugreek
aSignificant as compared to young control group
bSignificant as compared to adult control group
cSignificant as compared to young nitrate group
dSignificant as compared to adult nitrate group