. 2014 Dec 9;31(6):940–947. doi: 10.1093/bioinformatics/btu759

Table 1.

Most spatially variable proteins

RV#	CV#	Name	Subcellular localization	Cells
1	10	RPC82^a	Cytoplasm, nucleus^b	155
2	3	HSP78^a	Mitochondrion^c	86
3	7	RNR4^a	Cytoplasm, nucleus^d	145
4	39	ERG6	Lipid particle	83
5	137	LEU4	Cytoplasm, mitochondrion	195
6	2	ATP2	Mitochondrion	130
7	4	CBF1^a	Nucleus^b	72
8	146	ADE4^a	Cytoplasm	71
9	6	ALD5^a	Mitochondrion	123
10	230	ENA1^a	Cell periphery	130
11	129	DAD3	Spindle pole	192
12	32	ILV2^a	Mitochondrion	77
13	56	GIN4	Ambiguous, bud neck, cytoplasm, bud	182
14	151	BCY1^a	Cytoplasm, nucleus^c	198
15	437	UME1^a	Cytoplasm, nucleus^d	164
16	398	SRD1^a	Cytoplasm, nucleus	200
17	302	ACE2	Cytoplasm, nucleus, bud	148
18	274	VPS54	Punctate composite, early Golgi	95
19	21	LYS4	Mitochondrion	107
20	9	NET1	Nucleolus	206
21	266	EDE1	Punctate composite	168
22	1	ATP1	Mitochondrion	57
23	82	SPC34	Spindle pole	82
24	517	SNO1	Cytoplasm	66
25	80	MCM6	Cytoplasm, nucleus	100
26	247	TGL4	Lipid particle	159
27	331	SPO12^a	Nucleus	153
28	466	SEC10	Ambiguous, bud neck, cell periphery, bud	164
29	102	DAD1	Spindle pole	185
30	22	GCV2	Mitochondrion	56

The top 30 spatially variable proteins ranked by RV (RV#) are listed. Their ranks according to the CV (CV#) are also included for comparison. Subcellular localization categories as defined previously (Huh et al. 2003) are also indicated. The total number of mother–bud pairs available for the analysis (Cells) is also indicated. A complete listing of all proteins we analyzed is available as Supplementary Information.

^aProteins that actually appear variable upon visual inspection of the images.

^bSubsequent experiments indicated that variability is due to mixed genotypes.

^cSubsequent experiments were inconclusive.

^dSubsequent experiments confirmed variability in genetically identical cells.