There are errors in the legends for Figs. 3–6. The complete, correct figure legends for Figs. 3–6 are:
Fig 3. Forest plot and ORs with 95% CI of P2X7–762T/C polymorphism and pulmonary tuberculosis risk (CC vs. TT).
Fig 6. Forest plot and ORs with 95% CI of P2X7–762T/C polymorphism and pulmonary tuberculosis risk (CC vs. CT+TT).
Fig 4. Forest plot and ORs with 95% CI of P2X7–762T/C polymorphism and pulmonary tuberculosis risk (CT vs. TT).
Fig 5. Forest plot and ORs with 95% CI of P2X7–762T/C polymorphism and pulmonary tuberculosis risk (CC+CT vs. TT).
There are errors in Tables 1 and 3. Please see the corrected Tables 1 and 3 here.
Table 1. Characteristics of the case-control studies included in the meta-analysis.
| First Author | Year | Population | Genotyping method | Cases/Controls | Male Patients (%) | Male Controls (%) | Age of cases | Age of controls | Diagnosis method | Control source |
|---|---|---|---|---|---|---|---|---|---|---|
| Bahari et al. | 2013 | Caucasian (Iran) | ARMS-PCR | 150/150 | 38 | 34 | 48.97±21.2 | 45.36 ± 16.1 | Clinical symptoms, radiologic, smear, culture | Healthy individuals |
| Ben-Selma et al. | 2011 | African (Tunisia) | PCR-RFLP | 168/150 | 75.6 | 90 | 44(14–78) | 35(24–55) | Clinical examination, smear, culture | Healthy unrelated donors |
| Li et al. | 2002 | African (Gambia) | PCR-RFLP | 323/347 | 67.4 | 100 | 34.7±13.2 | 30.3±7.5 | Smear | Healthy unrelated donors |
| Mokrousov et al. | 2008 | Caucasian (Russia) | PCR-RFLP | 190/127 | 47.7 | 64.7 | 31.7±11.1 | 32.2±12.0 | Culture | Healthy unrelated donors |
| Nino-Moreno et al. | 2007 | Mixed (Mexico) | PCR-RFLP | 92/110 | 50 | DNR | 46.1±17.6 | 32.4±12.2 | Radiologic, culture | Healthy contacts |
| Sambasivan et al. | 2010 | Asian (India) | PCR-RFLP | 156/100 | 50.7 | 57 | 30.4±18.3 | 35.6±13.3 | Radiologic, smear | Healthy unrelated donors |
| Singla et al. | 2012 | Asian (India) | Allele-Specific PCR | 286/392 | 63 | 55 | 33.1± 15.4 | 36.4 ± 14.9 | DNR | Healthy unrelated individuals |
| Songane et al. | 2012 | Asian (Indonesia) | Sequencing | 842/844 | 53.4 | 53.2 | 33 | 33 | Clinical symptoms, radiologic, smear, culture | Healthy unrelated individuals |
Abbreviations and definitions: ARMS PCR, Amplification Refractory Mutation System-Polymerase Chain Reaction; PCR-RFLP, Restriction Fragment Length Polymorphism analysis of PCR amplified fragments;
DNR: data not reported.
Table 3. Meta-analysis of P2X7 gene-762T/C polymorphism and risk of pulmonary TB in each subgroup.
| Category | C vs. T | CC vs. TT | CT vs. TT | CC+CT vs. TT | CC vs. CT+TT |
|---|---|---|---|---|---|
| OR (95%CI), I2 (%) | OR (95%CI), I2 (%) | OR (95%CI), I2 (%) | OR (95%CI), I2 (%) | OR (95%CI), I2 (%) | |
| Ethnicity | |||||
| CaucasianAsian | 0.61 (0.26–1.45), 911.04 (0.70–1.55), 88 | 0.46 (0.06–3.39), 911.06 (0.43–2.59), 88 | 0.78 (0.15–4.17), 861.05 (0.56–1.98), 81 | 0.56 (0.08–3.87), 911.04 (0.50–2.15), 87 | 0.56 (0.29–1.10), 761.01 (0.66–1.53), 75 |
| African | 0.82 (0.57–1.17), 66 | 0.66 (0.31–1.41), 62 | 0.82 (0.63–1.08), 0 | 0.80 (0.56–1.16), 48 | 0.69 (0.37–1.31), 50 |
| Mixed | 0.70 (0.45–1.07) | 0.52 (0.20–1.34) | 0.71 (0.39–1.30) | 0.66 (0.38–1.16) | 0.60 (0.24–1.49) |
| Overall | 0.83 (0.65–1.07), 84 | 0.73 (0.44–1.22), 81 | 0.92 (0.68–1.24), 67 | 0.84 (0.59–1.19), 79 | 0.77 (0.57–1.04), 69 |
Reference
- 1. Yi L, Cheng D, Shi H, Huo X, Zhang K, Zhen G. (2014) A Meta-Analysis of P2X7 Gene-762T/C Polymorphism and Pulmonary Tuberculosis Susceptibility. PLoS ONE 9(5): e96359 doi: 10.1371/journal.pone.0096359 [DOI] [PMC free article] [PubMed] [Google Scholar]