Table 3.
White matter regions | Carotid-femoral PWV | Baroreflex sensitivity | |||
---|---|---|---|---|---|
β ± SE | P-value | β ± SE | P-value | ||
Global white matter | 0.38 ± 0.12 | <0.01 | −0.39 ± 0.10 | 0.001 | |
Corpus callosum | genu | 0.32 ± 0.17 | 0.07 | −0.24 ± 0.14 | 0.10 |
body | 0.31 ± 0.16 | 0.055 | −0.12 ± 0.13 | 0.37 | |
splenium | 0.36 ± 0.18 | 0.055 | −0.39 ± 0.15 | 0.01 | |
Corona radiata | anterior | 0.30 ± 0.14 | 0.03 | −0.30 ± 0.11 | 0.01 |
superior | 0.28 ± 0.15 | 0.07 | −0.28 ± 0.13 | 0.04 | |
posterior | 0.47 ± 0.15 | <0.01 | −0.32 ± 0.12 | 0.01 | |
Internal capsule | anterior limb | 0.18 ± 0.17 | 0.29 | −0.16 ± 0.14 | 0.25 |
posterior limb | 0.24 ± 0.16 | 0.14 | −0.04 ± 0.13 | 0.78 | |
retrolenticular part | 0.37 ± 0.17 | 0.03 | −0.28 ± 0.14 | 0.047 | |
External capsule | 0.29 ± 0.16 | 0.07 | −0.24 ± 0.13 | 0.08 | |
Superior longitudinal fasciculus | 0.38 ± 0.17 | 0.04 | −0.23 ± 0.15 | 0.13 |
Bold: P-value<0.05. The mean values of radial diffusivity were extracted from the global and regional white matter fiber tracts that associated with both carotid-femoral PWV and baroreflex sensitivity (see the bottom right of Figure 1). All models adjusted for age, sex, education level, systolic blood pressure, and total brain volume of white matter hyperintensity. Total brain volume of white matter hyperintensity was log-transformed before entered in the model. β=standardized regression coefficient, PWV=pulse wave velocity, and SE=standard error