Figure 3. β1 integrins promote the development of larger GFP-expressing tumors in the bone microenvironment in vivo.

A: Schematic overview of the in vivo bone colonization experiment using the hTEBC model. B: Representative images and quantification of in vivo whole-body fluorescent imaging data over time. C: Images and quantification of ex vivo fluorescent imaging data at the experimental endpoint. Caliper measurements of tumor volume after excision. Data are represented as mean ± standard error.