Table 1. Demographic, pathological and molecular data of patients.
Demographic data | |
---|---|
Median age (range) | 58.5 (46.0–66.0) |
Sex | |
Men | 84 (64%) |
Women | 48 (36%) |
Pathological characteristics | |
Tumour resection | |
Gross total | 26 (21%) |
Subtotal | 68 (55%) |
Partial | 12 (10%) |
Biopsy | 17 (14%) |
Tumour grade1 | |
I | 9 (7%) |
II | 14 (10%) |
III | 26 (20%) |
IV | 83 (63%) |
Tumour lineage | |
Astrocytic | 96 (73%) |
Oligodendroglial (OD) | 29 (22%) |
Astrocytic with OD differentiation | 7 (5%) |
Ki-67 grade | |
Low | 60 (47%) |
Intermediate | 51 (40%) |
High | 16 (13%) |
P53 expression | |
Low-Intermediate (≤ 60% cells) | 97 (77.6%) |
High (> 60% cells) | 28 (22.4%) |
Gene methylation | |
EPB41L3 | |
Yes | 29 (29%) |
No | 71 (71%) |
RASSF2 | |
Yes | 10 (10.6%) |
No | 84 (89.4%) |
TSP-1 | |
Yes | 58 (50%) |
No | 57 (50%) |
Grade according to the World Health Organization (WHO) grading system