Video 2. NTD-strap anti-correlated lid conformational changes.
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DOI: 10.7554/eLife.03487.013
A morph between two conformations of Hsp90, from the Apo state with cis-protomer interactions between NTD and strap, to the nucleotide bound closed state where the strap makes trans-protomer interactions. This morph demonstrates the significant number of contacts that are lost and then reformed to accommodate movement of the NTD to form the NTD-dimerization interface. (PDB codes 2IOQ, 4IVG, 4IPE).