There are errors in the third sentence of the Abstract. The third sentence should instead be two separate sentences, which should read as follows: However, some patients are non-responsive to this therapy, eventually become refractory to therapy, or may develop harmful side-effects. Alterations in the microbiota that are associated with the lack of TNF could be a contributing cause of the therapeutic insufficiency seen in some patients.
Reference
- 1. Jones-Hall YL, Kozik A, Nakatsu C (2015) Ablation of Tumor Necrosis Factor Is Associated with Decreased Inflammation and Alterations of the Microbiota in a Mouse Model of Inflammatory Bowel Disease. PLoS ONE 10(3): e0119441 doi:10.1371/journal.pone.0119441 [DOI] [PMC free article] [PubMed] [Google Scholar]
