Table 1. Baseline characteristics of the participants*.
Characteristic | Unadjusted Data | Data adjusted with use of inverse probability weighting | ||||
---|---|---|---|---|---|---|
CRP and leptin levels
|
P value | CRP and leptin levels
|
P value | |||
Low (N=5493) | High (N=766) | Low (N=5493) | High (N=766) | |||
Age (yr) | 47.1±18.9 | 53.1±17.6 | <0.001 | 47.9±18.5 | 50.4±21.6 | 0.16 |
Male sex (%) | 46.9 | 43.6 | 0.082 | 46.1 | 39.4 | 0.067 |
Race | <0.001 | 0.91 | ||||
Non-Hispanic white | 42.6 | 41.0 | 42.4 | 41.2 | ||
Non-Hispanic black | 26.1 | 34.5 | 27.5 | 29 | ||
Mexican American | 26.9 | 21.8 | 26.0 | 24.8 | ||
Other | 4.4 | 2.7 | 4.1 | 5.0 | ||
Body-mass index† | 26.3±5.0 | 34.0±6.3 | <0.001 | 27.3±5.7 | 29.2±6.2 | <0.001 |
Waist circumference (cm) | 90.9±13.0 | 109.8±12.9 | <0.001 | 93.4±14.3 | 98.2±14.8 | <0.001 |
History of heart failure (%) | 2.4 | 5.1 | <0.001 | 2.9 | 5.4 | 0.11 |
History of myocardial infarction (%) | 3.1 | 8.5 | <0.001 | 3.9 | 5.8 | 0.26 |
Cerebrovascular disease (%) | 2.3 | 4.4 | <0.001 | 2.7 | 4.8 | 0.19 |
Intermittent claudication (%) | 0.7 | 1.4 | 0.029 | 0.8 | 0.8 | 0.96 |
Hypertension (%) | 31.8 | 54.4 | <0.001 | 34.9 | 42.0 | 0.052 |
Dyslipidemia | 52.7 | 70.0 | <0.001 | 54.9 | 62.8 | 0.088 |
Angina (%) | <0.001 | 0.080 | ||||
None | 96.2 | 91.9 | 95.5 | 91.9 | ||
Grade I | 2.3 | 4.3 | 2.6 | 5.4 | ||
Grade II | 1.5 | 3.8 | 1.9 | 2.7 | ||
Diabetes (%) | <0.001 | 0.16 | ||||
None | 89.8 | 77.4 | 88.2 | 85.7 | ||
Any | 9.9 | 21.3 | 11.4 | 13.9 | ||
Requiring insulin | 0.4 | 1.3 | 0.4 | 0.4 | ||
Chronic kidney disease (%) | 22.3 | 34.9 | <0.001 | 24.2 | 29.2 | 0.082 |
Chronic lung disease (%) | 10.8 | 15.3 | <0.001 | 11.3 | 12.0 | 0.75 |
Smoking status (%) | <0.001 | 0.53 | ||||
Never smoker | 50.4 | 46.6 | 50.0 | 52.2 | ||
Former smoker | 23.8 | 31.2 | 24.7 | 25.9 | ||
Current smoker | 25.8 | 22.2 | 25.3 | 21.8 | ||
Family history of myocardial infarction | 8.5 | 8.1 | 0.70 | 8.4 | 6.9 | 0.30 |
Plus-minus values are means ± SDs
The body-mass index is the weight in kilograms divided by the square of the height in meters