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. 2015 Feb 13;156(5):942–950. doi: 10.1097/j.pain.0000000000000135

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© 2015 International Association for the Study of Pain

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Convergent receptive field (RF) areas from periorbital skin were enlarged in ocular neurons of dry eye disease (DE) rats 14 days after surgery. (A) Example of RF area of a wide dynamic range (WDR) unit recorded at the Vi/Vc transition. The center white region indicates average field size for WDR units in sham rats; hashed area indicates the RF area for this WDR unit from a DE rat. (B) Average RF area for neurons at the Vi/Vc transition of: sham rats, NS (n = 4) and WDR (n = 5); DE rats, NS (n = 5) and WDR (n = 5). (C) Average RF area for neurons in superficial laminae at the Vc/C1 region of: sham rats, NS (n = 6) and WDR (n = 5) units; DE rats, NS (n = 5) and WDR (n = 6) units. (D) Average RF area for WDR units in deep laminae at the Vc/C1 region. Sham, n = 11, DE, n = 11. a = P < 0.05, b = P < 0.01 vs sham.