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. 2015 Mar 10;89(7):4040. doi: 10.1128/JVI.03670-14

Correction for Noack et al., How Viruses Hijack the ERAD Tuning Machinery

Julia Noack a, Riccardo Bernasconi a, Maurizio Molinari a,b
PMCID: PMC4403389  PMID: 25759492

AUTHOR CORRECTION

Volume 88, no. 18, p. 10272–10275, 2014. Our Gem summarized recent findings on how Nidovirales and Flaviviridae may subvert the membrane of the endoplasmic reticulum (ER) for replication. In particular, we described how viruses coopt ER-derived membranes containing regulators of protein degradation to generate replication platforms.

Pages 10272–10273, column 2, paragraph 2: The paragraph beginning “Our group recently described” should be deleted. Two of the papers discussed there (references 3 and 4, i.e., Bernasconi R, Galli C, Noack J, Bianchi S, de Haan CA, Reggiori F, Molinari M. Mol. Cell 46:809–819, 2012, http://dx.doi.org/10.1016/j.molcel.2012.04.017, and Bernasconi R, Galli C, Kokame K, Molinari M. Mol. Cell 52:783–793, 2013, http://dx.doi.org/10.1016/j.molcel.2013.10.016) have been retracted. Western blot data showing that misfolded proteins expressed in the ER affect composition and stability of the ER-associated degradation (ERAD) machinery were not accurately reported in the retracted articles. While all other information in the Gem is correct, the specific example of the client-regulated ERAD tuning mechanism that we selected based on references 3 and 4 should not be considered unless further experimental evidence becomes available. For appropriate examples of ERAD tuning, please refer to reference 7 (Bernasconi R, Molinari M. Curr. Opin. Cell Biol. 23:176–183, 2011, http://dx.doi.org/10.1016/j.ceb.2010.10.002).

Page 10273, Fig. 1: Figure 1 and its legend should be deleted.

Page 10275, column 1: References 3 and 4 should be deleted.

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