Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Biomaterials. 2015 Mar 23;53:574–582. doi: 10.1016/j.biomaterials.2015.02.070

Figure 5.

Figure 5

A) H&E images of spleen tissue of animals treated with silica nanoparticles at 1 and 4 weeks. Increased levels of macrophages and multinucleated cells are present in the spleen at both 1 and 4 weeks. However, overall inflammatory effects are minimal, as a function of silica nanoparticle treatment. B) H&E images of liver tissue of animals treated with silica nanoparticles at 1 and 4 weeks. Increased levels of vacuolization (increased white space) are present in the liver at both 1 and 4 weeks. However, overall inflammatory effects are minimal as a result of silica nanoparticle treatment.