Table 1.
Baseline characteristics of study population
| HCV negative (n=920,531) |
HCV positive (n=100,518) |
|
|---|---|---|
| Age (years) | 55±13 | 53±8 |
| Gender (male) | 842,483 (92) | 96,537 (96) |
| Race: | ||
| White | 646,650 (75) | 58,887 (60) |
| African-American | 177,160 (20) | 35,129 (36) |
| Hispanic | 21,452 (2) | 2,158 (2) |
| Other Race | 20,693 (2) | 1,674 (2) |
| Marital status: | ||
| Married | 441,452 (50) | 30,332 (31) |
| Single | 123,439 (14) | 17,714 (18) |
| Divorced | 272,946 (31) | 44,066 (46) |
| Widow | 43,926 (5) | 4,251 (4) |
| Other sociodemographic: | ||
| Income (USD) | 21,111 (11,455–32,858) | 13,952 (9,361–27,615) |
| Non-adherent to medical interventions* | 71,415 (8) | 14,932 (15) |
| Miscallenous: | ||
| Baseline eGFR (ml/min./1.73m2) | 87±16 | 93±16 |
| BMI (kg/m2) | 29±6 | 28±5 |
| Systolic BP (mmHg) | 135±19 | 136±20 |
| Diastolic BP (mmHg) | 78±12 | 81±13 |
| Number of visits | 112 (59–201) | 154 (82–273) |
| Comorbidities: | ||
| Hypertension | 499,312 (54) | 53,230 (53) |
| Diabetes mellitus | 195,781 (21) | 21,152 (21) |
| Cardiovascular Disease** | 90,518 (10) | 7,410 (7) |
| Congestive Heart Failure | 29,635 (3) | 3,256 (3) |
| Cerebrovascular Disease | 43,770 (5) | 4,257 (4) |
| Peripheral Arterial Disease | 40,459 (4) | 4,130 (4) |
| Chronic Lung Disease | 155,446 (17) | 19,399 (19) |
| Dementia | 3,608 (0.4) | 372 (0.4) |
| Rheumatologic Disease | 14,733 (2) | 1,176 (1) |
| Liver Disease | 8,780 (1) | 8,100 (8) |
| All malignancies | 70,789 (8) | 6,622 (7) |
| AIDS/HIV | 9,743 (1) | 2,898 (3) |
| Depression | 115,524 (13) | 19,733 (20) |
| Medications: | ||
| Number of anti-hypertensive medications | 3 (2–4) | 3 (2–4) |
| PDC | 82±28 | 79±28 |
| ACEI or ARB used*** | 474,227 (52) | 52,837 (53) |
Dichotomous/dummy variables are presented as number of patients and percentage; continous variables are presented as mean±SD or median (interquartile range, IQR)
Defined as the presence of the ICD9-CM code V15.81 during any inpatient or outpatient encounter
Cardiovascular Disease was defined as acute myocardial infraction, angina, coronary artery disease, previous coronary artery bypass grafting or percutaneous coronary intervention
ACEI or ARB used any time during follow-up
Abbreviations: ACEI: Angiotensin converting enzyme inhibitor; AIDS: Acquired immundeficiency syndrome; ARB: Angiotensin receptor blocker; BMI: Body mass index; BP: Blood pressure; eGFR: Estimated glomerular filtration rate; HIV: Human Immundeficiency Virus; IQR: Interquartile range; PDC: Percentage of days covered; SD: Standard deviation