Fig. 5.
In vivo efficacy of NP Wtmn. Mice were innoculated with flank tumors of H69AR human SCLC cells. They were then treated with saline (black circles) or etoposide (open triangles). To evaluate free Wtmn as a chemosensitizer mice were treated with free Wtmn (closed blue squares) or free Wtmn + etoposide (open blue squares). To evaluate NP Wtmn as a chemosensitizer mice were treated with NP Wtmn (closed red circles) or NP Wtmn + etoposide (open red circles). * indicates significantly different AUC from all other treatment groups. N = 6–7 per treatment group.