Table 1. Classification (control vs. cancer) of blood plasma or serum samples with or without SERS ^a .

Class comparison	P-value	Significant
Plasma
Control vs. cancer	<0.001	Yes
Control vs. cancer (40 nm)	<0.001	Yes
Control vs. cancer (150 nm)	>0.05	No
Serum
Control vs. cancer	>0.05	No
Control vs. cancer (40 nm)	<0.001	Yes
Control vs. cancer (150 nm)	>0.05	No

^aFollowing acquisition of Raman spectra, one-way analysis of variance (ANOVA) with Bonferroni post-hoc tests were conducted on class means per sample to determine P-values for separation between cancer vs. non-cancer.