Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1956 Jun;35(6):619–626. doi: 10.1172/JCI103317

DIMINISHED PHENYLKETONURIA IN PHENYLPYRUVIC OLIGOPHRENIA AFTER ADMINISTRATION OF L-GLUTAMINE, L-GLUTAMATE OR L-ASPARAGINE1

Alton Meister 1,2,3,2, Sidney Udenfriend 1,2,3, Samuel P Bessman 1,2,3
PMCID: PMC441633  PMID: 13319499

Full text

PDF
619

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARMSTRONG M. D., ROBINSON K. S. On the excretion of indole derivatives in phenylketonuria. Arch Biochem Biophys. 1954 Sep;52(1):287–288. doi: 10.1016/0003-9861(54)90115-0. [DOI] [PubMed] [Google Scholar]
  2. ARMSTRONG M. D., TYLER F. H. Studies on phenylketonuria. I. Restricted phenylalanine intake in phenylketonuria. J Clin Invest. 1955 Apr;34(4):565–580. doi: 10.1172/JCI103105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BERRY J. P., WOOLF L. I. Estimation of phenylpyruvic acid. Nature. 1952 Feb 2;169(4292):202–203. doi: 10.1038/169202a0. [DOI] [PubMed] [Google Scholar]
  4. BICKEL H., GERRARD J., HICKMANS E. M. Influence of phenylalanine intake on phenylketonuria. Lancet. 1953 Oct 17;265(6790):812–813. doi: 10.1016/s0140-6736(53)90473-5. [DOI] [PubMed] [Google Scholar]
  5. BICKEL H., GERRARD J., HICKMANS E. M. The influence of phenylalanine intake on the chemistry and behaviour of a phenyl-ketonuric child. Acta Paediatr. 1954 Jan;43(1):64–77. doi: 10.1111/j.1651-2227.1954.tb04000.x. [DOI] [PubMed] [Google Scholar]
  6. BOREK E., BRECHER A., JERVIS G. A., WAELSCH H. Oligophrenia phenylpyruvica. II. Constancy of the metabolic error. Proc Soc Exp Biol Med. 1950 Oct;75(1):86–89. doi: 10.3181/00379727-75-18109. [DOI] [PubMed] [Google Scholar]
  7. BOSCOTT R. J., BICKEL H. Detection of some new abnormal metabolites in the urine of phenylketonuria. Scand J Clin Lab Invest. 1953;5(4):380–382. doi: 10.3109/00365515309094216. [DOI] [PubMed] [Google Scholar]
  8. DANCIS J., BALIS M. E. A possible mechanism for disturbance in tyrosine metabolism in phenylpyruvic oligophrenia. Pediatrics. 1955 Jan;15(1):63–66. [PubMed] [Google Scholar]
  9. JERVIS G. A. Excretion of phenylalanine and derivatives in phenylpyruvic oligophrenia. Proc Soc Exp Biol Med. 1950 Oct;75(1):83–86. doi: 10.3181/00379727-75-18108. [DOI] [PubMed] [Google Scholar]
  10. JERVIS G. A. Phenylpyruvic oligophrenia deficiency of phenylalanine-oxidizing system. Proc Soc Exp Biol Med. 1953 Mar;82(3):514–515. [PubMed] [Google Scholar]
  11. KLINGMULLER V., GAYER J., BRAMSTEDT F. Untersuchungen über den Stoffwechsel der L(+) -Glutaminsäure. II. Verschiebungen im Plasmaspiegel freier Aminosäuren nach Glutaminisäuregaben. Hoppe Seylers Z Physiol Chem. 1955 Apr 29;300(1-3):107–112. [PubMed] [Google Scholar]
  12. KLINGMULLER V., VOGELGESANG K. H. Untersuchungen über den Stoffwechsel der L (+) -Glutaminsäure. I. Allgemeinwirkungen und Veränderungen des Blutchemismus, insbesondere des Gehalts an Ketosäuren im Plasma nach Verabreichung von L(+) -Glutaminsäure in vivo. Hoppe Seylers Z Physiol Chem. 1955 Apr 29;300(1-3):97–106. [PubMed] [Google Scholar]
  13. KNOX W. E., LeMAY-KNOX M. The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid. Biochem J. 1951 Oct;49(5):686–693. doi: 10.1042/bj0490686. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. LA DU B. N., Jr, GREENBERG D. M. The tyrosine oxidation system of liver. I. Extracts of rat liver acetone powder. J Biol Chem. 1951 May;190(1):245–255. [PubMed] [Google Scholar]
  15. LEVINTOW L., MEISTER A. Reversibility of the enzymatic synthesis of glutamine. J Biol Chem. 1954 Jul;209(1):265–280. [PubMed] [Google Scholar]
  16. MEISTER A., SOBER H. A., TICE S. V. Determination of aspartic and glutamic acids by enzymatic decarboxylation. J Biol Chem. 1951 Apr;189(2):591–595. [PubMed] [Google Scholar]
  17. MEISTER A., TICE S. V. Transamination from glutamine to alpha-keto acids. J Biol Chem. 1950 Nov;187(1):173–187. [PubMed] [Google Scholar]
  18. MEISTER A. Transamination. Adv Enzymol Relat Subj Biochem. 1955;16:185–246. doi: 10.1002/9780470122617.ch4. [DOI] [PubMed] [Google Scholar]
  19. PRESCOTT B. A., BOREK E. Studies on oligophrenia phenylpyruvica; microbiological determination of L- and D-phenylalanine and of phenyl lactic acid. J Biol Chem. 1949 Nov;181(1):273–279. [PubMed] [Google Scholar]
  20. Penrose L., Quastel J. H. Metabolic studies in phenylketonuria. Biochem J. 1937 Feb;31(2):266–274. doi: 10.1042/bj0310266. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. SCHEPARTZ B., BOYLE A. Transamination as a step in tyrosine metabolism. J Biol Chem. 1951 Nov;193(1):293–298. [PubMed] [Google Scholar]
  22. SCHWERIN P., BESSMAN S. P., WAELSCH H. The uptake of glutamic acid and glutamine by brain and other tissues of the rat and mouse. J Biol Chem. 1950 May;184(1):37–44. [PubMed] [Google Scholar]
  23. UDENFRIEND S., BESSMAN S. P. The hydroxylation of phenylalanine and antipyrine in phenylpyruvic oligophrenia. J Biol Chem. 1953 Aug;203(2):961–966. [PubMed] [Google Scholar]
  24. UDENFRIEND S., COOPER J. R. Assay of L-phenylalanine as phenylethylamine after enzymatic decarboxylation; application to isotopic studies. J Biol Chem. 1953 Aug;203(2):953–960. [PubMed] [Google Scholar]
  25. WAELSCH H. Glutamic acid and cerebral function. Adv Protein Chem. 1951;6:299–341. doi: 10.1016/s0065-3233(08)60506-9. [DOI] [PubMed] [Google Scholar]
  26. WEIL-MALHERBE H. Significance of glutamic acid for the metabolism of nervous tissue. Physiol Rev. 1950 Oct;30(4):549–568. doi: 10.1152/physrev.1950.30.4.549. [DOI] [PubMed] [Google Scholar]
  27. WOOLF L. I., GRIFFITHS R., MONCRIEFF A. Treatment of phenylketonuria with a diet low in phenylalanine. Br Med J. 1955 Jan 8;1(4905):57–64. doi: 10.1136/bmj.1.4905.57. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. WOOLF L. I., VULLIAMY D. G. Phenylketonuria with a study of the effect upon it of glutamic acid. Arch Dis Child. 1951 Dec;26(130):487–494. doi: 10.1136/adc.26.130.487. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES