Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1959 Nov;38(11):2073–2086. doi: 10.1172/JCI103985

THE MEASUREMENT OF PULMONARY DIFFUSING CAPACITY FOR CARBON MONOXIDE BY A REBREATHING METHOD*,†

Benjamin M Lewis 1,2, Tai-Hon Lin 1,2, Frances E Noe 1,2,‡, Ernest J Hayford-Welsing 1,2,§, Erma Flaherty 1,2
PMCID: PMC441794  PMID: 14416493

Full text

PDF
2073

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AUSTRIAN R., McCLEMENT J. H., RENZETTI A. D., Jr, DONALD K. W., RILEY R. L., COURNAND A. Clinical and physiologic features of some types of pulmonary diseases with impairment of alveolar-capillary diffusion; the syndrome of "alveolar-capillary block". Am J Med. 1951 Dec;11(6):667–685. doi: 10.1016/0002-9343(51)90019-8. [DOI] [PubMed] [Google Scholar]
  2. BATES D. V., BOUCOT N. G., DORMER A. E. The pulmonary diffusing capacity in normal subjects. J Physiol. 1955 Aug 29;129(2):237–252. doi: 10.1113/jphysiol.1955.sp005350. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BATES D. V., KNOTT J. M., CHRISTIE R. V. Respiratory function in emphysema in relation to prognosis. Q J Med. 1956 Jan;25(97):137–157. [PubMed] [Google Scholar]
  4. BATES D. V. The measurement of the pulmonary diffusing capacity in the presence of lung disease. J Clin Invest. 1958 Apr;37(4):591–605. doi: 10.1172/JCI103642. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BICKELMANN A. G., BURWELL C. S., ROBIN E. D., WHALEY R. D. Extreme obesity associated with alveolar hypoventilation; a Pickwickian syndrome. Am J Med. 1956 Nov;21(5):811–818. doi: 10.1016/0002-9343(56)90094-8. [DOI] [PubMed] [Google Scholar]
  6. BLAKEMORE W. S., FORSTER R. E., MORTON J. W., OGILVIE C. M. A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide. J Clin Invest. 1957 Jan;36(1 Pt 1):1–17. doi: 10.1172/JCI103402. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. COURNAND A., RICHARDS D. W., Jr, BADER R. A., BADER M. E., FISHMAN A. P. The oxygen cost of breathing. Trans Assoc Am Physicians. 1954;67:162–173. [PubMed] [Google Scholar]
  8. DONALD K. W., RENZETTI A., RILEY R. L., COURNAND A. Analysis of factors affecting concentrations of oxygen and carbon dioxide in gas and blood of lungs; results. J Appl Physiol. 1952 Jan;4(7):497–525. doi: 10.1152/jappl.1952.4.7.497. [DOI] [PubMed] [Google Scholar]
  9. FILLEY G. F., MACINTOSH D. J., WRIGHT G. W. Carbon monoxide uptake and pulmonary diffusing capacity in normal subjects at rest and during exercise. J Clin Invest. 1954 Apr;33(4):530–539. doi: 10.1172/JCI102923. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FORSTER R. E. Exchange of gases between alveolar air and pulmonary capillary blood: pulmonary diffusing capacity. Physiol Rev. 1957 Oct;37(4):391–452. doi: 10.1152/physrev.1957.37.4.391. [DOI] [PubMed] [Google Scholar]
  11. FORSTER R. E., FOWLER W. S., BATES D. V. Considerations on the uptake of carbon monoxide by the lungs. J Clin Invest. 1954 Aug;33(8):1128–1134. doi: 10.1172/JCI102986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. FORSTER R. E., FOWLER W. S., BATES D. V., VAN LINGEN B. The absorption of carbon monoxide by the lungs during breath-holding. J Clin Invest. 1954 Aug;33(8):1135–1145. doi: 10.1172/JCI102987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KJERULF-JENSEN K., KRUHØFFER P. The lung diffusion coefficient for carbon monoxide in patients with lung disorders, as determined by C14O. Acta Med Scand. 1954;150(5):395–406. doi: 10.1111/j.0954-6820.1954.tb18642.x. [DOI] [PubMed] [Google Scholar]
  14. KRUHØFFER P. Studies on the lung diffusion coefficient for carbon monoxide in normal human subjects by means of C14O. Acta Physiol Scand. 1954 Nov;32(2-3):106–123. doi: 10.1111/j.1748-1716.1954.tb01160.x. [DOI] [PubMed] [Google Scholar]
  15. Krogh M. The diffusion of gases through the lungs of man. J Physiol. 1915 May 12;49(4):271–300. doi: 10.1113/jphysiol.1915.sp001710. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. LEWIS B. M., LIN T. H., NOE F. E., KOMISARUK R. The measurement of pulmonary capillary blood volume and pulmonary membrane diffusing capacity in normal subjects; the effects of exercise and position. J Clin Invest. 1958 Jul;37(7):1061–1070. doi: 10.1172/JCI103687. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. MARSHALL R. A comparison of methods of measuring the diffusing capacity of the lungs for carbon monoxide; investigation by fractional analysis of the alveolar air. J Clin Invest. 1958 Mar;37(3):394–408. doi: 10.1172/JCI103619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. McNEILL R. S., RANKIN J., FORSTER R. F. The diffusing capacity of the pulmonary membrane and the pulmonary capillary blood volume in cardiopulmonary disease. Clin Sci. 1958 Aug;17(3):465–482. [PubMed] [Google Scholar]
  19. RILEY R. L., COURNAND A., DONALD K. W. Analysis of factors affecting partial pressures of oxygen and carbon dioxide in gas and blood of lungs; methods. J Appl Physiol. 1951 Aug;4(2):102–120. doi: 10.1152/jappl.1951.4.2.102. [DOI] [PubMed] [Google Scholar]
  20. ROUGHTON F. J., FORSTER R. E., CANDER L. Rate at which carbon monoxide replaces oxygen from combination with human hemoglobin in solution and in the red cell. J Appl Physiol. 1957 Sep;11(2):269–276. doi: 10.1152/jappl.1957.11.2.269. [DOI] [PubMed] [Google Scholar]
  21. ROUGHTON F. J., FORSTER R. E. Relative importance of diffusion and chemical reaction rates in determining rate of exchange of gases in the human lung, with special reference to true diffusing capacity of pulmonary membrane and volume of blood in the lung capillaries. J Appl Physiol. 1957 Sep;11(2):290–302. doi: 10.1152/jappl.1957.11.2.290. [DOI] [PubMed] [Google Scholar]
  22. STONE D. J., SCHWARTZ M. J., GREEN R. A. Fatal pulmonary insufficiency due to radiation effect upon the lung. Am J Med. 1956 Aug;21(2):211–226. doi: 10.1016/0002-9343(56)90054-7. [DOI] [PubMed] [Google Scholar]
  23. WILLIAMS M. H., Jr Pulmonary function in Boeck's sarcoid. J Clin Invest. 1953 Sep;32(9):909–913. doi: 10.1172/JCI102809. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES