Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1960 Jul;39(7):1119–1130. doi: 10.1172/JCI104127

THE EFFECT OF ESTROGENS UPON THE PERIPHERAL METABOLISM OF THYROXINE *,†

J Thomas Dowling 1,2,3,4,5,‡, Norbert Freinkel 1,2,3,4,5, Sidney H Ingbar 1,2,3,4,5
PMCID: PMC441857  PMID: 13817901

Full text

PDF
1119

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BECKERS C., LULLING J., DE VISSCHER M. Influence de la folliculine sur le métabolisme de la radiothyroxine. Acta Endocrinol (Copenh) 1959 Feb;30(2):242–246. [PubMed] [Google Scholar]
  2. BEIERWALTES W. H., ROBBINS J. Familial increase in the thyroxine-binding sites in serum alpha globulin. J Clin Invest. 1959 Oct;38:1683–1688. doi: 10.1172/JCI103946. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BERSON S. A., YALOW R. S. Quantitative aspects of iodine metabolism: the exchangeable organic iodine pool, and the rates of thyroidal secretion, peripheral degradation and fecal excretion, of endogenously synthesized organically bound iodine. J Clin Invest. 1954 Nov;33(11):1533–1552. doi: 10.1172/JCI103032. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CRISPELL K. R., COLEMAN J. A study of the relative binding capacity of plasma proteins, intact human red cells, and human red cell stroma for radioactive I-131 labeled L-thyroxine. J Clin Invest. 1956 May;35(5):475–480. doi: 10.1172/JCI103299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CRUCHARD S., VANNOTTI A., MAHAIM C., DECKELMANN J. The in-vitro effect of methylthiouracil and oestradiol monophosphate on the conversion of thyroxine to triiodothyronine by kidney slices. Lancet. 1955 Oct 29;269(6896):906–907. doi: 10.1016/s0140-6736(55)92535-6. [DOI] [PubMed] [Google Scholar]
  6. DOISY R. J., LARDY H. A. Effect of certain steroids on metabolic rate of hyperthyroid rats. Am J Physiol. 1957 Jul;190(1):142–146. doi: 10.1152/ajplegacy.1957.190.1.142. [DOI] [PubMed] [Google Scholar]
  7. DOWLING J. T., FREINKEL N., INGBAR S. H. Effect of diethylstilbestrol on the binding of thyroxine in serum. J Clin Endocrinol Metab. 1956 Nov;16(11):1491–1506. doi: 10.1210/jcem-16-11-1491. [DOI] [PubMed] [Google Scholar]
  8. DOWLING J. T., FREINKEL N., INGBAR S. H. The influence of extracellular thyroxine-binding protein upon the accumulation of thyroxine by tissue slices. J Clin Invest. 1957 Jan;36(1 Pt 1):25–37. doi: 10.1172/JCI103406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. DOWLING J. T., FREINKEL N., INGBAR S. H. Thyroxine-binding by sera of pregnant women, newborn infants, and women with spontaneous abortion. J Clin Invest. 1956 Nov;35(11):1263–1276. doi: 10.1172/JCI103381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. DOWLING J. T., INGBAR S. H., FREINKEL N. Failure of diethylstilbestrol to affect thyroidal accumulation and renal clearance of I-131. J Clin Endocrinol Metab. 1959 Oct;19:1245–1251. doi: 10.1210/jcem-19-10-1245. [DOI] [PubMed] [Google Scholar]
  11. ENGBRING N. H., ENGSTROM W. W. Effects of estrogen and testosterone on circulating thyroid hormone. J Clin Endocrinol Metab. 1959 Jul;19(7):783–796. doi: 10.1210/jcem-19-7-783. [DOI] [PubMed] [Google Scholar]
  12. ENGSTROM W. W., MARKARDT B. Influence of estrogen on thyroid function. J Clin Endocrinol Metab. 1954 Feb;14(2):215–222. doi: 10.1210/jcem-14-2-215. [DOI] [PubMed] [Google Scholar]
  13. FEDERMAN D. D., ROBBINS J., RALL J. E. Effects of methyl testosterone on thyroid function, thyrozine metabolism, and thyroxine-binding protein. J Clin Invest. 1958 Jul;37(7):1024–1030. doi: 10.1172/JCI103683. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. FELDMAN J. D. Effect of estrogen on the peripheral utilization of thyroid hormones. Am J Physiol. 1957 Jan;188(1):30–34. doi: 10.1152/ajplegacy.1956.188.1.30. [DOI] [PubMed] [Google Scholar]
  15. FREEDBERG A. S., HAMOLSKY M. W., STEIN M. The thyroid hormone-plasma protein complex in man. II. A new in vitro method for study of uptake of labelled hormonal components by human erythrocytes. J Clin Endocrinol Metab. 1957 Jan;17(1):33–43. doi: 10.1210/jcem-17-1-33. [DOI] [PubMed] [Google Scholar]
  16. FREINKEL N., INGBAR S. H. ACTH, cortisone and the metabolism of iodine. Metabolism. 1956 Nov;5(6 Pt 1):652–666. [PubMed] [Google Scholar]
  17. GORDON A. H., GROSS J., O'CONNOR D., PITT-RIVERS R. Nature of the circulating thyroid hormone-plasma protein complex. Nature. 1952 Jan 5;169(4288):19–20. doi: 10.1038/169019a0. [DOI] [PubMed] [Google Scholar]
  18. GUIDRY M. A., SEGALOFF A., ALTSCHUL A. M. The effect of a-estradiol, some of its esters and estrone on the respiration of tissue homogenates. Endocrinology. 1952 Jan;50(1):29–36. doi: 10.1210/endo-50-1-29. [DOI] [PubMed] [Google Scholar]
  19. INGBAR S. H., FREINKEL N. Simultaneous estimation of rates of thyroxine degradation and thyroid hormone synthesis. J Clin Invest. 1955 Jun;34(6):808–819. doi: 10.1172/JCI103136. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. INGBAR S. H., FREINKEL N. Studies of thyroid function and the peripheral metabolism of I 131-labeled thyroxine in patients with treated Graves disease. J Clin Invest. 1958 Nov;37(11):1603–1614. doi: 10.1172/JCI103753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. INGBAR S. H. Pre-albumin: a thyroxinebinding protein of human plasma. Endocrinology. 1958 Aug;63(2):256–259. doi: 10.1210/endo-63-2-256. [DOI] [PubMed] [Google Scholar]
  22. Larson F., Deiss W. P., Albright E. C. Localization of Protein-bound Radioactive Iodine by Filter Paper Electrophoresis. Science. 1952 Jun 6;115(2997):626–627. doi: 10.1126/science.115.2997.626. [DOI] [PubMed] [Google Scholar]
  23. MYANT N. B. Relation between the biliary clearance rate of thyroxine and the binding of thyroxine by the serum proteins. J Physiol. 1957 Feb 15;135(2):426–441. doi: 10.1113/jphysiol.1957.sp005721. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. RALL J. E. Iodine compounds in the blood and urine of man. J Clin Endocrinol Metab. 1950 Sep;10(9):996–1006. doi: 10.1210/jcem-10-9-996. [DOI] [PubMed] [Google Scholar]
  25. RASMUSSEN H. Thyroxine metabolism in the nephrotic syndrome. J Clin Invest. 1956 Jul;35(7):792–799. doi: 10.1172/JCI103331. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. ROBBINS J., NELSON J. H. Thyroxinebinding by serum protein in pregnancy and in the newborn. J Clin Invest. 1958 Feb;37(2):153–159. doi: 10.1172/JCI103593. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. ROBBINS J., RALL J. E., PETERMANN M. L. Thyroxine-binding by serum and urine proteins in nephrosis; qualitative aspects. J Clin Invest. 1957 Sep;36(9):1333–1342. doi: 10.1172/JCI103532. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. ROBBINS J., RALL J. E. The interaction of thyroid hormones and protein in biological fluids. Recent Prog Horm Res. 1957;13:161–208. [PubMed] [Google Scholar]
  29. SOLOMON D. H. Factors affecting the fractional rate of release of radioiodine from the thyroid gland in man. Metabolism. 1956 Nov;5(6 Pt 1):667–681. [PubMed] [Google Scholar]
  30. STERLING K., CHODOS R. B. Radiothyroxine turnover studies in myxedema, thyrotoxicosis, and hypermetabolism without endocrine disease. J Clin Invest. 1956 Jul;35(7):806–813. doi: 10.1172/JCI103333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. VOLWILER W., GOLDSWORTHY P. D., MACMARTIN M. P., WOOD P. A., MACKAY I. R., FREMONT-SMITH K. Biosynthetic determination with radioactive sulfur of turn-over rates of various plasma proteins in normal and cirrhotic man. J Clin Invest. 1955 Jul;34(7 Pt 1):1126–1146. doi: 10.1172/JCI103162. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. WADE R., JONES H. W., Jr Effect of progesterone on oxidative phosphorylation. J Biol Chem. 1956 Jun;220(2):553–562. [PubMed] [Google Scholar]
  33. YAMAZAKI E., SLINGERLAND D. W. The in vitro metabolism of thryoxine, triiodothyronine and their acetic and propionic acid analogues. Endocrinology. 1959 Jan;64(1):126–135. doi: 10.1210/endo-64-1-126. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES