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. 1964 Sep;43(9):1813–1823. doi: 10.1172/JCI105055

A Biochemical Study of Human Skin Collagen and the Relation between Intra- and Intermolecular Cross-Linking *

Paul Bornstein 1,†, Karl A Piez 1
PMCID: PMC441982  PMID: 14207773

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALTGELT K., HODGE A. J., SCHMITT F. O. Gamma tropocollagen: a reversibly denaturable collagen macromolecule. Proc Natl Acad Sci U S A. 1961 Dec 15;47:1914–1924. doi: 10.1073/pnas.47.12.1914. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BAKERMAN S., HERSH R. T. EXTRACTION FROM HUMAN SKIN OF SOLUBLE COLLAGEN MOLECULES CONTAINING ONLY BETA COMPONENTS. Nature. 1964 Jan 11;201:190–191. doi: 10.1038/201190b0. [DOI] [PubMed] [Google Scholar]
  3. BAKERMAN S. Quantitative extraction of acid-soluble human skin collagen with age. Nature. 1962 Oct 27;196:375–376. doi: 10.1038/196375a0. [DOI] [PubMed] [Google Scholar]
  4. BORNSTEIN P., MARTIN G. R., PIEZ K. A. INTERMOLECULAR CROSS-LINKING OF COLLAGEN AND THE IDENTIFICATION OF A NEW BETA-COMPONENT. Science. 1964 Jun 5;144(3623):1220–1221. doi: 10.1126/science.144.3623.1220. [DOI] [PubMed] [Google Scholar]
  5. BOUCEK R. J., NOBLE N. L., KAO K. Y., ELDEN H. R. The effects of age, sex, and race upon the acetic acid fractions of collagen (human biopsy-connective tissue). J Gerontol. 1958 Jan;13(1):2–9. doi: 10.1093/geronj/13.1.2. [DOI] [PubMed] [Google Scholar]
  6. CLAUSEN B. Influence of age on connective tissue. Hexosamine and hydroxyproline in human aorta, myocardium, and skin. Lab Invest. 1962 Mar;11:229–234. [PubMed] [Google Scholar]
  7. EASTOE J. E. The amino acid composition of mammalian collagen and gelatin. Biochem J. 1955 Dec;61(4):589–600. doi: 10.1042/bj0610589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. GRASSMANN W., HANNIG K., ENGEL J. [Quantitative behavior between alpha- and beta-components of denatured soluble collagen in ultracentrifugation as well as a description of a more rapidly sedimentably gamma-component]. Hoppe Seylers Z Physiol Chem. 1961 Jun 21;324:284–288. doi: 10.1515/bchm2.1961.324.1.284. [DOI] [PubMed] [Google Scholar]
  9. GROSS J. An intermolecular defect of collagen in experimental lathyrism. Biochim Biophys Acta. 1963 Jul 16;74:314–316. doi: 10.1016/0006-3002(63)91374-x. [DOI] [PubMed] [Google Scholar]
  10. HARKNESS R. D. Biological functions of collagen. Biol Rev Camb Philos Soc. 1961 Nov;36:399–463. doi: 10.1111/j.1469-185x.1961.tb01596.x. [DOI] [PubMed] [Google Scholar]
  11. HARRINGTON W. F., VON HIPPEL P. H. The structure of collagen and gelatin. Adv Protein Chem. 1961;16:1–138. doi: 10.1016/s0065-3233(08)60028-5. [DOI] [PubMed] [Google Scholar]
  12. JACKSON D. S., BENTLEY J. P. On the significance of the extractable collagens. J Biophys Biochem Cytol. 1960 Feb;7:37–42. doi: 10.1083/jcb.7.1.37. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KUEHN K., ZIMMER E., WAYKOLE P., FIETZEK P. DIE WIRKUNG VON ALKALI AUF KOLLAGEN. DIE ANDERUNG DES LADUNGSMUSTERS DER TROPOKOLLAGEN-MOLEKUELE SOWIE DIE SPALTUNG DER INTRA- UND INTERMOLEKULAREN BINDUNGEN. Hoppe Seylers Z Physiol Chem. 1963;333:209–217. doi: 10.1515/bchm2.1963.333.1.209. [DOI] [PubMed] [Google Scholar]
  14. LEVENE C. I. Studies on the mode of action of lathyrogenic compounds. J Exp Med. 1962 Aug 1;116:119–130. doi: 10.1084/jem.116.2.119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. MARTIN G. R., GROSS J., PIEZ K. A., LEWIS M. S. On the intramolecular cross-linking of collagen in lathyritic rats. Biochim Biophys Acta. 1961 Nov 11;53:599–601. doi: 10.1016/0006-3002(61)90227-x. [DOI] [PubMed] [Google Scholar]
  16. MILCH R. A. Biochemical studies on the pathogenesis of collagen tissue changes in alcaptonuria. Clin Orthop. 1962;24:213–229. [PubMed] [Google Scholar]
  17. OREKHOVICH V., SHPIKITER V., KASAKOVA O., MAZOUROV V. The incorporation of C14-labeled glycine into the alpha- and beta-components of procollagen. Arch Biochem Biophys. 1959 Dec;85:554–556. doi: 10.1016/0003-9861(59)90524-7. [DOI] [PubMed] [Google Scholar]
  18. OREKHOVITCH V. N., CHPIKITER V. O., MAZOUROV V. I., KOUNINA O. V. [Precollagens. Classification, metabolism, action of proteases]. Bull Soc Chim Biol (Paris) 1960;42:505–518. [PubMed] [Google Scholar]
  19. PIEZ K. A., LEWIS M. S., MARTIN G. R., GROSS J. Subunits of the collagen molecule. Biochim Biophys Acta. 1961 Nov 11;53:596–598. doi: 10.1016/0006-3002(61)90226-8. [DOI] [PubMed] [Google Scholar]
  20. PIEZ K. A., MORRIS L. A modified procedure for the automatic analysis of amino acids. Anal Biochem. 1960 Nov;1:187–201. doi: 10.1016/0003-2697(60)90045-2. [DOI] [PubMed] [Google Scholar]
  21. PIEZ K. A., WEISS E., LEWIS M. S. The separation and characterization of the alpha- and beta-components of calf skin collagen. J Biol Chem. 1960 Jul;235:1987–1991. [PubMed] [Google Scholar]
  22. PROCKOP D. J., UDENFRIEND S. A specific method for the analysis of hydroxyproline in tissues and urine. Anal Biochem. 1960 Nov;1:228–239. doi: 10.1016/0003-2697(60)90050-6. [DOI] [PubMed] [Google Scholar]
  23. Rice R. V. REAPPEARANCE OF CERTAIN STRUCTURAL FEATURES OF NATIVE COLLAGEN AFTER THERMAL TRANSFORMATION. Proc Natl Acad Sci U S A. 1960 Sep;46(9):1186–1194. doi: 10.1073/pnas.46.9.1186. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. SCHLEYER M. [Separation of the alpha- and beta-components of tropocollagen. The amino acid sequence of collagen. V]. Hoppe Seylers Z Physiol Chem. 1962 Sep 6;329:97–104. doi: 10.1515/bchm2.1962.329.1.97. [DOI] [PubMed] [Google Scholar]
  25. VEIS A., COHEN J. Reversible transformation of gelatin to the collagen structure. Nature. 1960 May 28;186:720–721. doi: 10.1038/186720a0. [DOI] [PubMed] [Google Scholar]
  26. VEIS A., DRAKE M. P. The introduction of intramolecular cocalent cross-linkages into ichthyocol tropocollagen with monofunctional aldehydes. J Biol Chem. 1963 Jun;238:2003–2011. [PubMed] [Google Scholar]

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