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. 1964 Nov;43(11):2017–2025. doi: 10.1172/JCI105076

The Effect of Partial Hydrogenation of Dietary Fats, of the Ratio of Polyunsaturated to Saturated Fatty Acids, and of Dietary Cholesterol upon Plasma Lipids in Man *

B Arthur Erickson 1,2, Robert H Coots 1,2, Fred H Mattson 1,2, Albert M Kligman 1,2
PMCID: PMC441990  PMID: 14223915

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2017

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AHRENS E. H., Jr, BLANKENHORN D. H., TSALTAS T. T. Effect on human serum lipids of substituting plant for animal fat in diet. Proc Soc Exp Biol Med. 1954 Aug-Sep;86(4):872–878. doi: 10.3181/00379727-86-21260. [DOI] [PubMed] [Google Scholar]
  2. AHRENS E. H., Jr, INSULL W., Jr, BLOMSTRAND R., HIRSCH J., TSALTAS T. T., PETERSON M. L. The influence of dietary fats on serum-lipid levels in man. Lancet. 1957 May 11;272(6976):943–953. doi: 10.1016/s0140-6736(57)91280-1. [DOI] [PubMed] [Google Scholar]
  3. ANDERSON J. T., GRANDE F., KEYS A. Essential fatty acids, degree of unsaturation, and effect of corn (maize) oil on the serum-cholesterol level in man. Lancet. 1957 Jan 12;272(6959):66–68. doi: 10.1016/s0140-6736(57)90253-2. [DOI] [PubMed] [Google Scholar]
  4. ANDERSON J. T., GRANDE F., KEYS A. Hydrogenated fats in the diet and lipids in the serum of man. J Nutr. 1961 Dec;75:388–394. doi: 10.1093/jn/75.4.388. [DOI] [PubMed] [Google Scholar]
  5. BEVERIDGE J. M., CONNELL W. F., MAYER G. A. Dietary factors affecting the level of plasma cholesterol in humans: the role of fat. Can J Biochem Physiol. 1956 May;34(3):441–455. [PubMed] [Google Scholar]
  6. BEVERIDGE J. M., CONNELL W. F., MAYER G. A., FIRSTBROOK J. B., DEWOLFE M. S. The effects of certain vegetable and animal fats on the plasma lipids of humans. J Nutr. 1955 Jun 10;56(2):311–320. doi: 10.1093/jn/56.2.311. [DOI] [PubMed] [Google Scholar]
  7. BEVERIDGE J. M., CONNELL W. F. The effect of commercial margarines on plasma cholesterol levels in man. Am J Clin Nutr. 1962 May;10:391–397. doi: 10.1093/ajcn/10.5.391. [DOI] [PubMed] [Google Scholar]
  8. BEVERIDGE J. M., CONNEL W. F., MAYER G. A., HAUST H. L. Plant sterols, degree of unsaturation, and hypocholesterolemic action of certain fats. Can J Biochem Physiol. 1958 Sep;36(9):895–911. [PubMed] [Google Scholar]
  9. BRONTE-STEWART B., ANTONIS A., EALES L., BROCK J. F. Effects of feeding different fats on serum-cholesterol level. Lancet. 1956 Apr 28;270(6922):521–526. doi: 10.1016/s0140-6736(56)90592-x. [DOI] [PubMed] [Google Scholar]
  10. CONNOR W. E., HODGES R. E., BLEILER R. E. Effect of dietary cholesterol upon serum lipids in man. J Lab Clin Med. 1961 Mar;57:331–342. [PubMed] [Google Scholar]
  11. CONNOR W. E., HODGES R. E., BLEILER R. E. The serum lipids in men receiving high cholesterol and cholesterol-free diets. J Clin Invest. 1961 May;40:894–901. doi: 10.1172/JCI104324. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. GRASSO S., GUNNING B., IMAICHI K., MICHAELS G., KINSELL L. Effects of natural and hydrogenated fats of approximately equal dilenoic acid content upon plasma lipids. Metabolism. 1962 Aug;11:920–924. [PubMed] [Google Scholar]
  13. HASHIM S. A., ARTEAGA A., VAN ITALLIE T. B. Effect of a saturated medium-chain triglyceride on serum-lipids in man. Lancet. 1960 May 21;1(7134):1105–1108. doi: 10.1016/s0140-6736(60)90986-7. [DOI] [PubMed] [Google Scholar]
  14. HASHIM S. A., CLANCY R. E., HEGSTED D. M., STARE F. J. Effect of mixed fat formula feeding on serum cholesterol level in man. Am J Clin Nutr. 1959 Jan-Feb;7(1):30–34. doi: 10.1093/ajcn/7.1.30. [DOI] [PubMed] [Google Scholar]
  15. HORLICK L., CRAIG B. M. Effect of long-chain polyunsaturated and saturated fatty acids on the serum-lipids of man. Lancet. 1957 Sep 21;273(6995):566–569. doi: 10.1016/s0140-6736(57)90059-4. [DOI] [PubMed] [Google Scholar]
  16. HORLICK L. Studies on the regulation of serum-cholesterol levels in man; the effects of corn oil, ethyl stearate, hydrogenated soybean oil, and nicotinic acid when added to a very low-fat basal diet. Lab Invest. 1959 May-Jun;8(3):723–735. [PubMed] [Google Scholar]
  17. HORLICK L. The effect of artificial modification of food on the serum cholesterol level. Can Med Assoc J. 1960 Dec 3;83:1186–1192. [PMC free article] [PubMed] [Google Scholar]
  18. JOLLIFFE N. Dietary factors regulating serum cholesterol. Metabolism. 1961 Jul;10:497–513. [PubMed] [Google Scholar]
  19. KEYS A., ANDERSON J. T., GRANDE F. Prediction of serum-cholesterol responses of man to changes in fats in the diet. Lancet. 1957 Nov 16;273(7003):959–966. doi: 10.1016/s0140-6736(57)91998-0. [DOI] [PubMed] [Google Scholar]
  20. KINSELL L. W., MICHAELS G. D., PARTRIDGE F. W., BOLING L. A., BALCH H. E., COCHRANE G. C. Effect upon serum cholesterol and phospholipids of diets containing large amounts of vegetable fat. J Clin Nutr. 1953 Mar-Apr;1(3):224–231. doi: 10.1093/ajcn/1.3.224. [DOI] [PubMed] [Google Scholar]
  21. KINSELL L. W., PARTRIDGE J., BOLING L., MARGEN S., MICHAELS G. Dietary modification of serum cholesterol and phospholipid levels. J Clin Endocrinol Metab. 1952 Jul;12(7):909–913. doi: 10.1210/jcem-12-7-909. [DOI] [PubMed] [Google Scholar]
  22. MALMROS H., WIGAND G. The effect on serum-cholesterol of diets containing different fats. Lancet. 1957 Jul 6;273(6984):1–7. doi: 10.1016/s0140-6736(57)90568-8. [DOI] [PubMed] [Google Scholar]
  23. MALMROS H., WIGAND G. Treatment of hypercholesteremia. Minn Med. 1955 Dec;38(12):864–870. [PubMed] [Google Scholar]
  24. MATTSON F. H., VOLPENHEIN R. A. The specific distribution of fatty acids in the glycerides of vegetable fats. J Biol Chem. 1961 Jul;236:1891–1894. [PubMed] [Google Scholar]
  25. MORSE E. H., BICKNELL E., LEWIS E. P., MERROW S. B., NEWHALL C. A. Relation of dietary fats to blood lipids in young men. J Am Diet Assoc. 1962 Oct;41:323–327. [PubMed] [Google Scholar]
  26. VAN HANDEL E. Suggested modifications of the micro determination of triglycerides. Clin Chem. 1961 Jun;7:249–251. [PubMed] [Google Scholar]
  27. WILCOX E. B., GALLOWAY L. S. Serum cholesterol and different dietary fats. J Am Diet Assoc. 1961 Mar;38:227–230. [PubMed] [Google Scholar]
  28. ZILVERSMIT D. B., DAVIS A. K. Microdetermination of plasma phospholipids by trichloroacetic acid precipitation. J Lab Clin Med. 1950 Jan;35(1):155–160. [PubMed] [Google Scholar]

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