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. 1965 Jan;44(1):8–20. doi: 10.1172/JCI105129

Intracellular Acid-Base Regulation. I. The Response of Muscle Cells to Changes in CO2 Tension or Extracellular Bicarbonate Concentration *

Sheldon Adler 1,2,, Arlene Roy 1,2, Arnold S Relman 1,2,
PMCID: PMC442014  PMID: 14254260

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ADLER S., ROY A., RELMAN A. S. INTRACELLULAR ACID-BASE REGULATION. II. THE INTERACTION BETWEEN CO-2 TENSION AND EXTRACELLULAR BICARBONATE IN THE DETERMINATION OF MUSCLE CELL PH. J Clin Invest. 1965 Jan;44:21–30. doi: 10.1172/JCI105123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CALDWELL P. C. Studies on the internal pH of large muscle and nerve fibres. J Physiol. 1958 Jun 18;142(1):22–62. doi: 10.1113/jphysiol.1958.sp005998. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CONWAY E. J. Nature and significance of concentration relations of potassium and sodium ions in skeletal muscle. Physiol Rev. 1957 Jan;37(1):84–132. doi: 10.1152/physrev.1957.37.1.84. [DOI] [PubMed] [Google Scholar]
  4. IRVINE R. O., SAUNDERS S. J., MILNE M. D., CRAWFORD M. A. Gradients of potassium and hydrogen ion in potassiumdeficient voluntary muscle. Clin Sci. 1961 Feb;20:1–18. [PubMed] [Google Scholar]
  5. KIBLER R. F., O'NEILL R. P., ROBIN E. D. INTRACELLULAR ACID-BASE RELATIONS OF DOG BRAIN WITH REFERENCE TO THE BRAIN EXTRACELLULAR VOLUME. J Clin Invest. 1964 Mar;43:431–443. doi: 10.1172/JCI104928. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. RELMAN A. S., GORHAM G. W., LEVINSKY N. G. The relation between external potassium concentration and the electrolyte content of isolated rat muscle in the steady state. J Clin Invest. 1961 Feb;40:386–393. doi: 10.1172/JCI104265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. ROBIN E. D. Of men and mitochondria--intracellular and subcellular acid-base relations. N Engl J Med. 1961 Oct 19;265:780–785. doi: 10.1056/NEJM196110192651605. [DOI] [PubMed] [Google Scholar]
  8. ROGERS T. A. Tissue buffering in rat diaphragm. Am J Physiol. 1957 Nov;191(2):363–366. doi: 10.1152/ajplegacy.1957.191.2.363. [DOI] [PubMed] [Google Scholar]
  9. SCHWARTZ W. B., JENSON R. L., RELMAN A. S. The disposition of acid administered to sodium-depleted subjects: the renal response and the role of the whole body buffers. J Clin Invest. 1954 Apr;33(4):587–597. doi: 10.1172/JCI102930. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. SINGER R. B., CLARK J. K., BARKER E. S., CROSLEY A. P., Jr, ELKINTON J. R. The acute effects in man of rapid intravenous infusion of hypertonic sodium bicarbonate solution. I. Changes in acid-base balance and distribution of the excess buffer base. Medicine (Baltimore) 1955 Feb;34(1):51–95. doi: 10.1097/00005792-195502000-00003. [DOI] [PubMed] [Google Scholar]
  11. SNELL F. M., McINTYRE O. R. The effects of carbon dioxide and hydrogen ion on sodium transport in isolated frog skin. Biochim Biophys Acta. 1960 Jun 17;41:89–98. doi: 10.1016/0006-3002(60)90372-3. [DOI] [PubMed] [Google Scholar]
  12. STEGEMANN J. DER EINFLUSS VON KOHLENDIOXYDDRUCKEN AUF DAS INTERSTITIELLE PH DES ISOLIERTEN RATTENDIAPHRAGMAS. Pflugers Arch Gesamte Physiol Menschen Tiere. 1964 Mar 12;279:36–49. [PubMed] [Google Scholar]
  13. SWAN R. C., AXELROD D. R., SEIP M., PITTS R. F. Distribution of sodium bicarbonate infused into nephrectomized dogs. J Clin Invest. 1955 Dec;34(12):1795–1801. doi: 10.1172/JCI103234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. SWAN R. C., PITTS R. F. Neutralization of infused acid by nephrectomized dogs. J Clin Invest. 1955 Feb;34(2):205–212. doi: 10.1172/JCI103073. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Stella G. The combination of carbon dioxide with muscle: its heat of neutralization and its dissociation curve. J Physiol. 1929 Aug 28;68(1):49–66. doi: 10.1113/jphysiol.1929.sp002595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. TOBIN R. B. Plasma, extracellular and muscle electrolyte responses to acute metabolic acidosis. Am J Physiol. 1956 Jul;186(1):131–138. doi: 10.1152/ajplegacy.1956.186.1.131. [DOI] [PubMed] [Google Scholar]
  17. WADDELL W. J., BUTLER T. C. Calculation of intracellular pH from the distribution of 5,5-dimethyl-2,4-oxazolidinedione (DMO); application to skeletal muscle of the dog. J Clin Invest. 1959 May;38(5):720–729. doi: 10.1172/JCI103852. [DOI] [PMC free article] [PubMed] [Google Scholar]

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