TABLE II.

Distribution of 8q24 Genotypes in Relation to Prostate Cancer Risk in Men ≤65 Years

	Cases	Controls	OR	95% CI	P-value
rs1447295	(n = 156)	(n = 231)
rs1447295 (C allele)	0.68	0.65
rs1447295 (A allele)	0.32	0.35
rs1447295 (C/C)	74 (47.4)	97 (42.0)	1.00
rs1447295 (C/A)	63 (40.4)	108 (46.8)	0.76	0.50–1.18	0.22
rs1447295 (A/A)	19 (12.2)	26 (11.2)	0.96	0.49–1.86	0.89
rs1447295 (C/A) + (A/A)	82 (52.6)	134 (58.0)	0.80	0.53–1.21	0.29
rs16901979	(n = 151)	(n = 224)
rs16901979 (C allele)	0.43	0.55
rs16901979 (A allele)	0.57	0.45
rs16901979 (C/C)	28 (18.6)	77 (34.4)	1.00
rs16901979 (C/A)	73 (48.3)	91 (40.6)	2.21	1.30–3.75	0.003*
rs16901979 (A/A)	50 (33.1)	56 (25.0)	2.46	1.38–4.37	0.002*
rs16901979 (C/A) + (A/A)	123 (81.4)	157 (65.6)	2.30	1.40–3.77	0.001*
rs6983267	(n = 149)	(n = 225)
rs6983267 (G allele)	0.96	0.95
rs6983267 (T allele)	0.04	0.05
rs6983267 (G/G)	137 (91.9)	201 (89.3)	1.00
rs6983267 (G/T)	11 (7.4)	24 (10.7)	0.67	0.32–1.42	0.29
rs6983267 (T/T)	1 (0.7)	0 (0.0)	—	—	—
rs6983267 (G/T) + (T/T)	12 (8.1)	24 (10.7)	0.73	0.35–1.52	0.40

^*Significant predictors of prostate cancer risk.