TABLE V.

Frequency of T Allele (African Populations) and G Allele (European Populations) of SNP rs6983267

Study	No. of cases	No. of controls	Frequency in cases	Frequency in controls	OR	95% CI	P-value
African ancestry
Bunker et al. 2,3 (Tobago men)	343	426	0.05	0.06	0.83	0.53–1.29	0.40
Robbins et al. 14 (African Americans)	567	490	0.08	0.11	1.4 (associated with G allele)	0.9–2.4	0.123 0.068 (adju. for age and W.A. ancestry)
Cheng et al. 15 (African Americans)	89	89	0.09	0.11	1.15 (associated with G allele)	0.57–2.35	0.693
Salinas et al. 16 (African Americans)	145	78			0.57	0.28–1.18	0.13

	No. of cases	No. of controls	G allele	G allele	OR (GT genotype)	OR (GG genotype)	P-value
European ancestry
Yeager et al. 13 PLCO (G)	1,172	1,157	0.55	0.49	1.40 (1.14–1.73)	1.73 (1.37–2.19)	2.43 × 10−5
Yeager et al. 13 ACS	1,140	1,151	0.55	0.50	1.27 (1.03–1.56)	1.49 (1.18–1.89)	3.16 × 10−3
Yeager et al. 13 ATBC	894	896	0.57	0.51	1.26 (0.99–1.60)	1.66 (1.28–2.16)	1.89 × 10−3
Yeager et al. 13 FPCC	455	459	0.56	0.51	1.13 (0.81–1.59)	1.45 (1.00–2.10)	1.17 × 10−1
Yeager et al. 13 HPFS	625	636	0.57	0.51	1.15 (0.87–1.53)	1.58 (1.15–2.16)	9.54 × 10−3
Yeager et al. 13 ALL	4,284	4,299	0.56	0.50	1.26 (1.13–1.41)	1.58 (1.40–1.78)	9.42 × 10−13
Cheng et al. 15 (European Americans) (G)	417	417	0.56	0.50	1.39	1.14–1.70	0.001
Salinas et al. 16 (Caucasians)	1,258	1,238	0.45	0.50	0.91 (0.75–1.10) (GT genotype)	0.67 (0.54–0.85) (TT genotype)	0.0017