In Table 2, there are errors in the “Dominant,” “Recessive,” “Overdominant,” and “Allele frequency” rows. Please view the corrected table below.
Table 2. Genotype distribution of IL 18–137 G/C polymorphism in Controls, CAD patients and FDRS (N = 700).
| Model | Genotype | Controls N = 300 n (%) | CAD N = 300 n (%) | CAD Odds Ratio | FDRS N = 100 n (%) | FDRS Odds Ratio | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| χ2 | Odds ratio (95% CI) | p-Value | χ2 | Odds ratio(95% CI) | p-Value | |||||
| Co-dominant | GG | 176(58.7) | 168(56) | 0.001 | 1 | 0.99 | 65(65) | 2.34 | 1 | 0.12 |
| GC | 105(35) | 102(34) | 1.02 (0.72–1.44) | 25(25) | 0.64 (0.38–1.09) | |||||
| CC | 19(6.3) | 30(10) | 1.8 | 1.65 (0.90–3.05) | 0.17 | 10(10) | 2.38 | 1.43 (0.63–3.23) | 0.12 | |
| Dominant | GG | 176(58.7) | 168(56) | 0.33 | 1.12 | 0.56 | 65(65) | 1 | 0.76 | 0.31 |
| GC-CC | 124(41.3) | 132(44) | (0.81–1.54) | 35(35) | (0.48–1.22) | |||||
| Recessive | GG-GC | 281(93.7) | 270(90) | 2.22 | 1.64 | 0.13 | 90(90) | 1 | 1.64 | 0.31 |
| CC | 19(6.3) | 30(10) | (0.90–2.99) | 10(10) | (0.74–3.66) | |||||
| Overdominant | GG-CC | 195(65) | 198(66) | 0.02 | 0.96 | 0.86 | 75(75) | 2.9 | 0.62 | 0.08 |
| GC | 105(35) | 102(34) | (0.68–1.34) | 25(25) | (0.37–1.03) | |||||
| Log-Additive | - - - - | - - - - | - - - - | - - - - | 1.17 | 0.23 | - - - - | - - - - | 0.93 | 0.71 |
| (0.91–1.50) | (0.65–1.34) | |||||||||
| Allele frequency | G | 457(76) | 438(73) | 1.42 | 1.182 | 0.23 | 155(78) | 0.08 | 0.92 | 0.77 |
| C | 143(24) | 162(27) | (0.91–1.53) | 45(22) | (0.6295–1.354) | |||||
| Minor allele frequency | C | 0.24 | 0.27 | - - - - | 0.22 | - - - - | ||||
| HWE (p-value) | 0.53 | 0.019 | - - - - | 0.007 | - - - - | |||||
Additionally, in Fig 3, the line “Analysis of promoter binding site for IL-8 polymorphism” is erroneously included. Please view the corrected figure here.
Fig 3. Analysis of Promoter binding site for IL -18-137 G/C Polymorphism.
Reference
- 1. G RK, K MS, G KK, Kurapati M, M S, T MA, et al. (2015) Evaluation of Hs-CRP Levels and Interleukin 18 (-137G/C) Promoter Polymorphism in Risk Prediction of Coronary Artery Disease in First Degree Relatives. PLoS ONE 10(3): e0120359 doi: 10.1371/journal.pone.0120359 [DOI] [PMC free article] [PubMed] [Google Scholar]