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. Author manuscript; available in PMC: 2015 May 7.
Published in final edited form as: Neuropharmacology. 2010 Jan 6;58(7):972–980. doi: 10.1016/j.neuropharm.2009.12.017

Figure 7. Time course of BBB permeability post ischemia.

Figure 7

BBB permeability was measured in untreated animals using Evans blue as described in the legend to Figure 1, before and 1, 2 and 3 hours after induction of brain ischemia by mechanical occlusion. In second set of animals, three hours after induction of brain ischemia, BBB permeability was measured after rtPA was given alone or together with the 6- or 18-aa-Tyr PAI-1 derived peptides. The mean ± SEM of data from 12 animals/group is shown.