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. 2015 May 7;145(2):288–299. doi: 10.1111/imm.12447

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Published 2015. This article is a U.S. Government work and is in the public domain in the USA.

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Impact of antiretroviral therapy (ART) plus Env therapeutic immunization on plasma viral load rebound post-ART. Correlations between Gag (a and c) and Env-specific (b and d) interleukin-2 (IL-2) production by central memory (CM) CD4⁺ T cells at week 11 with plasma viral load levels at week 13. Graphs on top (a and b, n = 14) include all macaques in the study, whereas graphs on the bottom (c and d, n = 10) include Env-immunized macaques only. Spearman's correlation analysis was used to determine statistical significance.