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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Bone. 2014 Nov 29;72:92–100. doi: 10.1016/j.bone.2014.11.018

Figure 1. Loss of EP1 is protective against age-induced bone loss.

Figure 1

Three-dimensional microCT reconstructions of the metaphyseal femur [A] and L4 vertebrae [D] of WT and EP1−/− mice at 2-months, 6-months and 1-year of age. [B & E] Bone volume/total volume; [C & F] trabecular number, trabecular spacing, and trabecular thickness quantification of the femur and L4 vertebrae, respectively. N = 5 per group. Statistical analysis was performed using 2-way ANOVA followed by Dunnett’s test. (*) = p < 0.05 v.s. age-matched WT, (#) = p < 0.05 v.s. respective genotype at 2-months.