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. 1972 Jan;1(1):46–48. doi: 10.1128/aac.1.1.46

Four-Hour Microbiological Assay of Gentamicin in Serum1

Edward Warren a, Robert J Snyder a, John A Washington II a
PMCID: PMC444164  PMID: 4670428

Abstract

Since the microbiological assay of the antibiotic content of serum generally requires 18 to 24 hr of incubation, results of such procedures may not become available in time to make appropriate adjustments in subsequent dosages of antibiotic. A 4-hr bioassay for determining concentrations of gentamicin in serum has been developed in which Staphylococcus aureus ATCC 6538P is used as the test organism. Poured plates have yielded satisfactory results after storage at 4 C for 5 days. Results of the 4-hr procedure agree closely with those of a conventional 18-hr disc-plate assay performed with the same test organism.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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