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. 1972 Jan;1(1):73–77. doi: 10.1128/aac.1.1.73

Inhibitory Effects of Mitomycin-Related Compounds Lacking the C1-C2 Aziridine Ring

Carmen M Mercado 1, Maria Tomasz 1
PMCID: PMC444168  PMID: 4670432

Abstract

Three chemical derivatives of mitomycin C cause loss of viability, inhibition of deoxyribonucleic acid synthesis, and inhibition of cell division in bacteria. Each of these drugs lacks the C1-C2 aziridine ring previously postulated to be essential for the bactericidal effect of mitomycin C.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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