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. 1972 Sep;2(3):122–131. doi: 10.1128/aac.2.3.122

Cephamycins, a New Family of β-Lactam Antibiotics I. Production by Actinomycetes, Including Streptomyces lactamdurans sp. n1

E O Stapley 1,2, M Jackson 1,2, S Hernandez 1,2, S B Zimmerman 1,2, S A Currie 1,2, S Mochales 1,2, J M Mata 1,2, H B Woodruff 1,2, D Hendlin 1,2
PMCID: PMC444278  PMID: 4790552

Abstract

A number of actinomycetes isolated from soil were found to produce one or more members of a new family of antibiotics, the cephamycins, which are structurally related to cephalosporin C. The cephamycins were produced in submerged fermentation in a wide variety of media by one or more of eight different species of Streptomyces, including a newly described species, S. lactamdurans. These antibiotics exhibit antibacterial activity against a broad spectrum of bacteria which includes many that are resistant to the cephalosporins and penicillins.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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