Abstract
A method is described for phenotyping of isoniazid inactivators. After a test dose of isoniazid, free isoniazid and its acetyl derivative are estimated in urine by the same colorimetric reaction.
Full text
PDF![130](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74cb/444372/8181ea43a707/aac00343-0138.png)
![131](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74cb/444372/ef8c014b2208/aac00343-0139.png)
![132](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74cb/444372/4b7e11854c37/aac00343-0140.png)
![133](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/74cb/444372/46535cef0097/aac00343-0141.png)
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- EIDUS L., HAMILTON E. J. A NEW METHOD FOR THE DETERMINATION OF N-ACETYL ISONIAZID IN URINE OF AMBULATORY PATIENTS. Am Rev Respir Dis. 1964 Apr;89:587–588. doi: 10.1164/arrd.1964.89.4.587. [DOI] [PubMed] [Google Scholar]
- Eidus L., Harnanansingh A. M. A more sensitive spectrophotometric method for determination of isoniazid in serum or plasma. Clin Chem. 1971 Jun;17(6):492–494. [PubMed] [Google Scholar]
- Eidus L., Harnanansingh A. M., Jessamine A. G. Urine test for phenotyping isoniazid inactivators. Am Rev Respir Dis. 1971 Oct;104(4):587–591. doi: 10.1164/arrd.1971.104.4.587. [DOI] [PubMed] [Google Scholar]
- IWAINSKY H., GERLOFF W., SCHMIEDEL A. [The differentiation between isoniazid-inactivating and normally catabolizing patients by means of a simple test]. Beitr Klin Tuberk Spezif Tuberkuloseforsch. 1961;124:384–389. [PubMed] [Google Scholar]
- Jeanes C. W., Schaefer O., Eidus L. Inactivation of isoniazid by Canadian Eskimos and Indians. Can Med Assoc J. 1972 Feb 19;106(4):331–335. [PMC free article] [PubMed] [Google Scholar]
- MAIER N., MOISESCU V. EINE SCHNELLE METHODE ZUR BESTIMMUNG DER KONZENTRATION DES DURCH DIE NIEREN AUSGESCHIEDENEN INH. Beitr Klin Tuberk Spezif Tuberkuloseforsch. 1964 May 27;128:213–217. [PubMed] [Google Scholar]
- Russell D. W., Eidus L. Simplified isoniazid acetylator phenotyping. Can Med Assoc J. 1972 Jun 10;106(11):1155–1156. [PMC free article] [PubMed] [Google Scholar]
- Russell D. W. Simple method for determining isoniazid acetylator phenotype. Br Med J. 1970 Aug 8;3(5718):324–325. doi: 10.1136/bmj.3.5718.324. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TEICHMANN W., KOEHLER R. BEITRAG ZUR SCHNELLEN DIFFERENZIERUNG DES INDIVIDUELLEN INH-STOFFWECHSELS. Prax Pneumol. 1964 Aug;18:535–541. [PubMed] [Google Scholar]
- Venkataraman P., Eidus L., Tripathy S. P. Method for the estimation of acetylisoniazid in urine. Tubercle. 1968 Jun;49(2):210–216. doi: 10.1016/0041-3879(68)90023-8. [DOI] [PubMed] [Google Scholar]