TABLE 2.
Multivariable-Adjusted Associations Between Time Spent in MVPA at Age 11 Years and Adiposity and Cardiometabolic Risk Markers at Age 15 Years
| Variable | Non–Blood-Based Sample Outcomes (n = 4639) | ||
|---|---|---|---|
| Model 1a | Model 2b | Model 3c | |
| BMI SDS | −0.074 (–0.096 to –0.053) | −0.062 (–0.083 to –0.041) | 0.016 (0.004 to 0.028) |
| Body fat mass, % | −0.756 (–0.901 to –0.612) | −0.679 (–0.822 to –0.536) | −0.320 (–0.438 to –0.203) |
| Lean body mass, % | 1.150 (0.983 to 1.317) | 1.065 (0.899 to 1.231) | 0.082 (–0.29 to 0.192) |
| Waist, cmd | −0.008 (–0.010 to –0.005) | −0.007 (–0.009 to –0.004) | 0.002 (0.000 to 0.003) |
| SBP, mm Hg | −0.276 (–0.490 to –0.061) | −0.253 (–0.467 to 0.038) | −0.043 (–0.244 to 0.158) |
| DBP, mm Hg | −0.032 (–0.210 to 0.147) | −0.019 (–0.199 to 0.161) | 0.095 (–0.080 to 0.270) |
| Blood-Based Sample Outcomes (n = 2963) | |||
| Model 1a | Model 2b | Model 3c | |
| Triglycerides, mmol/Ld | −0.012 (–0.021 to –0.002) | −0.011 (–0.020 to –0.001) | −0.007 (–0.017 to 0.002) |
| HDL-C, mmol/Ld | 0.010 (0.005 to 0.015) | 0.009 (0.004 to 0.015) | 0.006 (0.001 to 0.011) |
| C-reactive protein, mg/Ld | −0.045 (–0.072 to –0.018) | −0.043 (–0.070 to –0.016) | −0.019 (–0.045 to 0.008) |
| Glucose, mmol/Ld | 0.000 (–0.002 to 0.002) | 0.000 (–0.002 to 0.002) | 0.000 (–0.002 to 0.002) |
| Insulin, IU/Ld | −0.034 (–0.046 to –0.022) | −0.032 (–0.044 to –0.021) | −0.024 (–0.036 to –0.013) |
| Total cholesterol, mmol/L | 0.006 (–0.010 to 0.021) | 0.006 (–0.010 to 0.021) | 0.007 (–0.008 to 0.023) |
| LDL-C, mmol/L | −0.002 (–0.016 to 0.011) | −0.002 (–0.015 to 0.012) | 0.002 (–0.011 to 0.016) |
| CMscore, SDe | −0.029 (–0.041 to –0.018) | −0.027 (–0.038 to –0.016) | −0.014 (–0.025 to –0.004) |
Coefficients represent the mean difference in the cardiometabolic risk indicator per 10-minute greater time spent in MVPA at age 11 years. Accelerometry, baseline cardiometabolic risk indicator, and Tanner stage data at age 13 years used for subjects with no accelerometry data at age 11 years.
Adjusted for gender, wear time at age 11 years, and age at measurement of cardiometabolic risk indicator.
Also adjusted for time between accelerometry data collection and measurement of cardiometabolic risk factors, paternal social class, birth weight, maternal BMI, Tanner stage at age 11 years, age at measurement of Tanner stage, and total energy intake at age 10 years.
Also adjusted for baseline cardiometabolic risk indicator at age 11 years (BMI used for blood-based outcomes).
These variables were log-transformed before analysis.
A composite z score compiled from 10 of the outcome variables.