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. 1973 Jul;4(1):11–15. doi: 10.1128/aac.4.1.11

Separation and Detection of Tetracyclines by High-Speed Liquid Chromatography

A G Butterfield 1, D W Hughes 1, N J Pound 1, W L Wilson 1
PMCID: PMC444497  PMID: 4791479

Abstract

The high-speed liquid chromatographic behavior of 15 tetracyclines on anion- and cation-exchange columns is described and illustrated by typical separations of a number of tetracycline derivatives on several systems, as well as by the resolution of tetracycline from its degradation products epi-, epianhydro-, and anhydrotetracycline. These serve as a basis for a rapid, convenient, and precise method for the direct detection of the tetracycline antibiotics and their degradation products.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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